Question 1

Which of the following best describes the difference between genotype and phenotype?

Accepted Answer

Genotype refers to the DNA sequence that controls a trait, while phenotype refers to the observable features of an organism.

Question 2

During oogenesis in humans, what is the main function of polar bodies?

Accepted Answer

To ensure the egg has the correct haploid chromosome number by discarding extra sets of chromosomes.

Question 3

Which stage of meiosis is characterized by the pairing of homologous chromosomes (synapsis)?

Accepted Answer

Prophase I

Question 4

A plant with genotype $Tt$ (where $T$ is tall and $t$ is short) is self-fertilized. What is the expected phenotypic ratio in the offspring?

Accepted Answer

$3:1$ (tall:short)

Question 5

Which of the following statements about mitochondrial inheritance is correct?

Accepted Answer

Mitochondrial DNA is maternally inherited; mothers pass it to all their children.

Question 6

If a cell has a diploid number of $2n = 8$, how many chromosomes will be present in each gamete after meiosis?

Accepted Answer

$4$

Question 7

Which of the following best explains Mendel's law of independent assortment?

Accepted Answer

Alleles for different genes segregate independently during gamete formation.

Question 8

A woman with genotype $AA$ for a gene and a man with genotype $aa$ have a child. What is the genotype of the child?

Accepted Answer

$Aa$

Question 9

Which process ensures that each daughter cell receives the same genetic content as the parent cell?

Accepted Answer

Mitosis

Question 10

In a pedigree analysis, which inheritance pattern is indicated if a trait is passed from mother to all her children, but not from father to children?

Accepted Answer

Mitochondrial inheritance

Question 11

Which of the following is true about homologous chromosomes?

Accepted Answer

They carry the same genes but may have different alleles.

Question 12

What is the expected genotypic ratio for a monohybrid cross between two heterozygous individuals ($Aa 	imes Aa$)?

Accepted Answer

$1:2:1$ (AA:Aa:aa)

Question 13

Which of the following events occurs during anaphase of mitosis?

Accepted Answer

Sister chromatids separate and move to opposite poles.

Question 14

A man with blood type AB and a woman with blood type O have a child. What are the possible blood types of their child?

Accepted Answer

A or B

Question 15

Which of the following best describes the function of spindle fibers during cell division?

Accepted Answer

They attach to chromosomes and help move them during mitosis and meiosis.

Question 16

If a primary oocyte in humans is arrested in prophase I before puberty, what triggers its completion of meiosis I?

Accepted Answer

Ovulation

Question 17

Which of the following is a result of crossing over during meiosis?

Accepted Answer

Unique combinations of parental chromosomes in gametes

Question 18

A pedigree shows a trait that appears in every generation and affects both males and females equally. What is the most likely inheritance pattern?

Accepted Answer

Autosomal dominant

Question 19

Which of the following best describes the outcome of meiosis II?

Accepted Answer

Separation of sister chromatids

Question 20

A testcross is performed by crossing an individual with an unknown genotype with which of the following?

Accepted Answer

A homozygous recessive individual

Foundations of Genetics: Key Concepts, Cell Division, and Mendelian Inheritance

Study Guide - Practice Questions