Question 1

Which ethical principle is most directly challenged by the proposal to require genetic testing for alcoholism before issuing a driver's license?

Accepted Answer

Autonomy

Question 2

Assuming alcoholism is purely genetic and the test is 100% accurate, which of the following best describes the predictive value of the test?

Accepted Answer

The test has a positive predictive value of 100%

Question 3

If the allele for alcoholism is present in 10% of the population, and the test is 100% accurate, what is the probability that a randomly selected individual who tests positive will become an alcoholic?

Accepted Answer

$$P = 1$$

Question 4

Which argument best supports the DAMM position against mandatory breathalyzer locks for individuals with the alcoholism allele?

Accepted Answer

It stigmatizes individuals based on genetic predisposition, not behavior.

Question 5

If the government does not archive DNA samples after testing, which genetic privacy concern is most mitigated?

Accepted Answer

Risk of genetic information being leaked to the public

Question 6

Which real-world precedent is most similar to the proposed breathalyzer lock policy for those with the alcoholism allele?

Accepted Answer

Requiring convicted drunk drivers to install ignition interlocks

Question 7

If the allele for alcoholism is dominant, and both parents are heterozygous ($$Aa$$), what is the probability that their child will inherit the allele?

Accepted Answer

$$P = 0.75$$

Question 8

Which of the following is a potential unintended consequence of implementing the proposed genetic testing policy?

Accepted Answer

Increased stigmatization of individuals with the alcoholism allele

Question 9

If the frequency of the alcoholism allele in the population is $$p = 0.2$$, what proportion of the population would be required to install breathalyzer locks under the proposed policy?

Accepted Answer

$$0.2$$

Question 10

Which of the following best illustrates a limitation of using genetic information for public policy decisions?

Accepted Answer

Genetic predisposition does not guarantee behavior.

Question 11

If the allele for alcoholism is recessive, and one parent is homozygous recessive ($$aa) $$and the other is heterozygous ($$Aa$$), what is the probability their child will inherit the alcoholism allele?

Accepted Answer

$$P = 0.5$$

Question 12

Which of the following is a valid argument in favor of the MADD proposal?

Accepted Answer

It ensures only those with a genetic predisposition are monitored, reducing unnecessary restrictions.

Question 13

If the test for the alcoholism allele is 100% accurate, what is the false positive rate?

Accepted Answer

0%

Question 14

Which concept is most relevant when considering whether to restrict rights based on genetic predisposition?

Accepted Answer

Genetic determinism

Question 15

If the government pays for breathalyzer locks, which economic principle is most relevant to evaluating the policy's cost-effectiveness?

Accepted Answer

Opportunity cost

Question 16

Which scenario best illustrates genetic discrimination?

Accepted Answer

Denying a driver’s license based on a positive alcoholism allele test

Question 17

If the allele for alcoholism is found on chromosome 4, which type of inheritance pattern would NOT be possible?

Accepted Answer

X-linked recessive

Question 18

Which of the following best describes the concept of 'stigmatization' in the context of the proposed policy?

Accepted Answer

Labeling individuals as dangerous based on genetic predisposition

Question 19

If the allele frequency for alcoholism is $$p = 0.3$$ and the population is in Hardy-Weinberg equilibrium, what is the expected proportion of individuals who are homozygous for the allele?

Accepted Answer

$$p^2 = 0.09$

Question 20

Which of the following is a potential benefit of the proposed policy from a public health perspective?

Accepted Answer

Reduction in deaths and injuries caused by drunk driving

Genetics, Ethics, and Public Policy: Analyzing Genetic Testing for Alcoholism

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