Principles of Genetics – Course Syllabus and Study Guide

Principles of Genetics (PCB3060) – Course Syllabus Study Notes

Course Overview

This course introduces the mechanisms of transmission of hereditary information, covering classical and modern genetics. Students will learn about Mendelian principles, gene mapping, population genetics, molecular genetics, and the genetic basis of diseases such as cancer.

• Mendelian Genetics: Study of inheritance patterns based on Gregor Mendel's laws.

• Classical Genetics: Includes chromosome theory, gene mapping, and extensions of Mendelian principles.

• Population Genetics: Analysis of genetic variation within populations and evolutionary processes.

• Molecular Genetics: Structure and function of DNA, gene expression, and regulation.

Key Topics Covered

• Transmission Genetics: Mechanisms by which genetic information is passed from one generation to the next.

• Gene Expression and Regulation: How genes are turned on/off and how this affects phenotype.

• Genetic Mapping: Techniques for locating genes on chromosomes.

• Mutation and Disease: How changes in DNA can lead to genetic disorders and cancer.

Course Learning Outcomes

• Understand and apply Mendelian and classical genetic principles.

• Describe the molecular basis of gene function and regulation.

• Analyze genetic data and solve problems using critical thinking.

• Evaluate the impact of genetics on health, disease, and society.

Textbook

• Concepts of Genetics by William Klug et al., 12th Edition, Pearson. ISBN: 9780134833707

Organization & Technology

• Lectures are delivered in-person and online (synchronous/asynchronous).

• Assignments and quizzes are completed via Canvas and Mastering Genetics (MG).

• Exams are administered online with secure proctoring tools.

Grading & Assessments

Assessment	Weight
1st Exam	13.3%
Midterm	13.3%
Final	13.3%
Quizzes	20%
Paper	20%
Assignments (including MG)	20%

Grade	Scale (%)
A	90 - 100
B	80 - 89
C	70 - 79
D	60 - 69
F	Below 60

Attendance & Participation

• Attendance is required for all scheduled classes and online meetings.

• Participation and punctuality are graded.

• No make-up for missed quizzes or exams; missed work receives a zero.

Student Success Tips

• Spend 1–2 hours outside of class for every hour spent in class.

• Review notes and textbook regularly; do not rely solely on class attendance.

• Form study groups and seek help when needed.

• Balance work and play to avoid burnout.

Support & Resources

• Remote learning support, Canvas, and campus resources are available.

• Students with disabilities should contact ACCESS SERVICES for accommodations.

General Education Learning Outcomes

• Communication: Listening, writing, and speaking skills.

• Numbers/Data Analysis: Ability to evaluate and process numerical data.

• Critical Thinking: Problem-solving using scientific information.

• Information Literacy: Locate, evaluate, and apply information.

• Technology Usage: Use emerging technologies effectively.

Example: Mendelian Genetics

• Law of Segregation: Each individual has two alleles for each gene, which segregate during gamete formation.

• Law of Independent Assortment: Genes for different traits assort independently during gamete formation.

• Punnett Square: Tool for predicting genotype and phenotype ratios.

Example Equation

Probability of a genotype in a monohybrid cross:

$P = \frac{\text{Number of desired genotype}}{\text{Total number of possible genotypes}}$

Additional info: These notes summarize the syllabus and provide a structured overview of the course content, expectations, and resources for success in Genetics (PCB3060).