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Ch. 27 Fluids & Electrolytes
Martini - Fundamentals of Anatomy & Physiology 11th Edition
Martini, Nath, Bartholomew11th EditionFundamentals of Anatomy & PhysiologyISBN: 9780136874089Non è quello che usi tu?Cambia libro di testo
Capitolo 26, Problema 9

Metabolic alkalosis occurs when:
(a) Bicarbonate ion concentrations become elevated
(b) A severe bicarbonate loss occurs
(c) The kidneys fail to excrete hydrogen ions
(d) Ketone bodies are generated in abnormally large quantities

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1
Step 1: Understand the definition of metabolic alkalosis. It is a condition where the pH of body fluids is elevated above normal due to an increase in bicarbonate (HCO3-) concentration or a loss of hydrogen ions (H+).
Step 2: Analyze option (a): 'Bicarbonate ion concentrations become elevated.' Since bicarbonate is a base, an increase in its concentration would raise the pH, leading to alkalosis. This aligns with the definition of metabolic alkalosis.
Step 3: Analyze option (b): 'A severe bicarbonate loss occurs.' Losing bicarbonate would reduce the base concentration, which would lower pH and cause acidosis, not alkalosis.
Step 4: Analyze option (c): 'The kidneys fail to excrete hydrogen ions.' Retaining hydrogen ions would increase acidity, causing acidosis rather than alkalosis.
Step 5: Analyze option (d): 'Ketone bodies are generated in abnormally large quantities.' Ketone bodies are acidic, so their accumulation leads to metabolic acidosis, not alkalosis.

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Metabolic Alkalosis

Metabolic alkalosis is a condition characterized by an elevated blood pH due to increased bicarbonate concentration or loss of hydrogen ions. It results in the blood becoming more alkaline, often caused by factors like excessive vomiting or diuretic use.
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02:17
Introduction to Metabolism

Bicarbonate Ion Role in Acid-Base Balance

Bicarbonate ions (HCO3-) act as a primary buffer in the blood, neutralizing acids to maintain pH balance. An increase in bicarbonate concentration raises blood pH, leading to alkalosis, while a decrease can cause acidosis.
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01:29
Acids and Bases

Kidney Function in Acid-Base Regulation

The kidneys regulate acid-base balance by excreting hydrogen ions and reabsorbing bicarbonate. Failure to excrete hydrogen ions can cause acidosis, while excessive bicarbonate retention or hydrogen ion loss can lead to alkalosis.
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01:29
Acids and Bases
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Domanda del libro di testo

The most important factor affecting the pH of body tissues is the concentration of:

(a) Lactic acid

(b) Ketone bodies, 

(c) Metabolic acids

(d) Carbon dioxide

(e) Hydrochloric acid

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Identify four hormones that mediate major physiological adjustments affecting fluid and electrolyte balance. What are the primary effects of each hormone?

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Domanda del libro di testo

Drinking a solution hypotonic to the ECF causes the ECF to:

(a) Increase in volume and become hypertonic to the ICF

(b) Decrease in volume and become hypertonic to the ICF

(c) Decrease in volume and become hypotonic to the ICF

(d) Increase in volume and become hypotonic to the ICF

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Domanda del libro di testo

Changes in the pH of body fluids are compensated for by all of the following except:

(a) An increase in urine output

(b) The carbonic acid–bicarbonate buffer system

(c) The phosphate buffer system

(d) Changes in the rate and depth of breathing

(e) Protein buffers

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The osmotic concentration of the ECF decreases if an individual gains water without a corresponding:

(a) Gain of electrolytes

(b) Loss of water

(c) Fluid shift from the ECF to the ICF

(d) All of these

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Domanda del libro di testo

Respiratory acidosis develops when the blood pH is:

(a) Increased due to a decreased blood P𝒸ₒ₂ level

(b) Decreased due to an increased blood P𝒸ₒ₂ level

(c) Increased due to an increased blood P𝒸ₒ₂ level

(d) Decreased due to a decreased blood P𝒸ₒ₂ level

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