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Ch. 22 The Lymphatic System and Immunity
Martini - Fundamentals of Anatomy & Physiology 11th Edition
Martini, Nath, Bartholomew11th EditionFundamentals of Anatomy & PhysiologyISBN: 9780136874089당신이 사용하는 게 아니라요?교과서 변경
22장, 문제 8

Perforins are proteins associated with the activity of
(a) T cells
(b) B cells
(c) NK cells
(d) Plasma cells

검증된 단계별 안내
1
Understand the role of perforins: Perforins are proteins that create pores in the membranes of target cells, leading to cell lysis and death.
Identify which immune cells use perforins: Perforins are primarily used by cytotoxic cells to destroy infected or abnormal cells.
Recall that T cells, specifically cytotoxic T lymphocytes (CTLs), use perforins to kill virus-infected cells.
Recognize that Natural Killer (NK) cells also use perforins to destroy target cells without prior sensitization.
Conclude that both T cells (cytotoxic) and NK cells are associated with perforin activity, but since the question asks for the best match, NK cells (option c) are the classic cells known for perforin-mediated cytotoxicity.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Perforins

Perforins are proteins that create pores in the membranes of target cells, leading to cell lysis. They are crucial in the immune response for destroying infected or abnormal cells by allowing entry of cytotoxic molecules.
추천 영상:
가이드 코스
6:21
Functions of Cytotoxic T Cells

Natural Killer (NK) Cells

NK cells are a type of lymphocyte involved in the innate immune system. They use perforins and granzymes to kill virus-infected cells and tumor cells without prior sensitization.
추천 영상:
가이드 코스
6:53
Natural Killer Cells

Cytotoxic T Cells

Cytotoxic T cells (a subset of T cells) recognize and kill infected or cancerous cells by releasing perforins and granzymes. They are part of the adaptive immune response and require antigen presentation for activation.
추천 영상:
가이드 코스
4:27
Review of Cytotoxic vs Helper T Cells