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Ch. 7 - DNA Structure and Replication
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
모든 교과서Sanders 3rd EditionCh. 7 - DNA Structure and Replication문제 9a
7장, 문제 9a

Consider the sequence 3'-ACGCTACGTC-5'.
What is the double-stranded sequence?

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Identify the given sequence as the 3' to 5' strand: 3'-ACGCTACGTC-5'.
Recall the base-pairing rules in DNA: Adenine (A) pairs with Thymine (T), and Cytosine (C) pairs with Guanine (G).
Write the complementary strand by pairing each base with its complement, ensuring the complementary strand is written in the 5' to 3' direction.
Reverse the complementary sequence to ensure it is properly oriented as 5' to 3'.
Combine the original strand and the complementary strand to represent the double-stranded DNA sequence, with the original strand on top and the complementary strand below.

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주요 개념

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DNA Structure

DNA is composed of two strands that form a double helix, with each strand consisting of nucleotides. Each nucleotide contains a phosphate group, a sugar, and a nitrogenous base. The bases pair specifically: adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). Understanding this structure is essential for determining complementary sequences.
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가이드 코스
06:25
DNA Structure

Complementary Base Pairing

Complementary base pairing is the principle that dictates how nucleotides pair in DNA. In a double-stranded DNA molecule, A pairs with T and C pairs with G. This pairing is crucial for accurately determining the complementary sequence of a given single-stranded DNA sequence, as it ensures the fidelity of genetic information.
추천 영상:
가이드 코스
03:49
Base Distortions

Directionality of DNA Strands

DNA strands have directionality, indicated by the 5' and 3' ends. The 5' end has a phosphate group, while the 3' end has a hydroxyl group. When determining the complementary sequence, it is important to maintain the correct orientation, as the complementary strand will run in the opposite direction (antiparallel) to the original strand.
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가이드 코스
05:02
Directionality
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교과서 질문

The following figure (Figure 1.6) presents simplified depictions of nucleotides containing deoxyribose, a nucleotide base, and a phosphate group. Use this simplified method of representation to illustrate the sequence 3'-AGTCGAT-5' and its complementary partner in a DNA duplex.

What kind of bonds join the C in one strand to the G in the complementary strand?

488
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교과서 질문

DNA polymerase III is the main DNA-synthesizing enzyme in bacteria. Describe how it carries out its role of elongating a strand of DNA.

551
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교과서 질문

The following figure (Figure 1.6) presents simplified depictions of nucleotides containing deoxyribose, a nucleotide base, and a phosphate group. Use this simplified method of representation to illustrate the sequence 3'-AGTCGAT-5' and its complementary partner in a DNA duplex.

How many hydrogen bonds are present in this DNA duplex?

526
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교과서 질문

Consider the sequence 3'-ACGCTACGTC-5'.

What is the total number of noncovalent bonds joining the nucleotides of the complementary strands?

595
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교과서 질문

The following figure (Figure 1.6) presents simplified depictions of nucleotides containing deoxyribose, a nucleotide base, and a phosphate group. Use this simplified method of representation to illustrate the sequence 3'-AGTCGAT-5' and its complementary partner in a DNA duplex.

How many phosphodiester bonds are present in this DNA duplex?

425
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교과서 질문

Consider the sequence 3'-ACGCTACGTC-5'.

What is the total number of covalent bonds joining the nucleotides in each strand?

943
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