Question 1

Which of the following best describes a physical property of a substance?

Accepted Answer

The melting point of the substance

Question 2

Which of the following is an example of a functional group isomer?

Accepted Answer

Ethyl alcohol and dimethyl ether

Question 3

Given the compounds $$\mathrm{C_2H_5OH}$$ and $$\mathrm{CH_3OCH_3}$$, which statement is true?

Accepted Answer

They are functional group isomers

Question 4

Which rule is used to assign priority to substituents on a chiral center?

Accepted Answer

Assign priority based on atomic number; higher atomic number gets higher priority

Question 5

Which of the following pairs are enantiomers?

Accepted Answer

Two compounds that are mirror images and non-superimposable

Question 6

What is the relationship between cis-2-butene and trans-2-butene?

Accepted Answer

They are geometric isomers

Question 7

Which of the following statements about diastereomers is correct?

Accepted Answer

Diastereomers have different physical and chemical properties

Question 8

A compound has two chiral centers. How many possible stereoisomers can it have?

Accepted Answer

$$2^2 = 4$

Question 9

Which of the following is NOT a criterion for two compounds to be considered enantiomers?

Accepted Answer

They must have different physical properties

Question 10

Which of the following is a correct statement about meso compounds?

Accepted Answer

Meso compounds have an internal plane of symmetry

Question 11

Which of the following best describes a chain isomer?

Accepted Answer

Compounds with the same molecular formula but different carbon skeletons

Question 12

Which property is used to distinguish between physical and chemical properties?

Accepted Answer

Physical properties can be observed without changing the substance's identity

Question 13

Which of the following is a correct application of the Cahn-Ingold-Prelog priority rules?

Accepted Answer

Assign priority to substituents based on atomic number, then move outward if there is a tie

Question 14

Which of the following pairs of compounds are NOT isomers?

Accepted Answer

propane and butane

Question 15

Which of the following is a real-world application of optical isomers?

Accepted Answer

The effectiveness of a drug can depend on its chirality

Question 16

Which of the following statements about geometric isomers is correct?

Accepted Answer

Geometric isomers arise due to restricted rotation around a double bond

Question 17

Which of the following is a correct example of a pair of diastereomers?

Accepted Answer

Two compounds with two chiral centers, differing at only one center

Question 18

Which of the following is NOT a physical property?

Accepted Answer

Ability to react with sodium metal

Question 19

Which of the following is a correct statement about functional group isomers?

Accepted Answer

They have the same molecular formula but different functional groups

Question 20

Which of the following is a correct method to distinguish between enantiomers and diastereomers?

Accepted Answer

Enantiomers are mirror images; diastereomers are not

Isomerism and Stereochemistry in Organic Chemistry

Study Guide - Practice Questions