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Ch. 20 - The Molecular Revolution: Biotechnology, Genomics, and New Frontiers
Freeman - Biological Science 7th Edition
Freeman7th EditionBiological ScienceISBN: 9783584863285Not the one you use?Change textbook
Chapter 20, Problem 4

The human genome size is 3 billion base pairs, and the size of the baker's yeast genome, a single-celled organism, is 12 million base pairs. Therefore, the predicted genome size for another single-celled organism, an amoeba,
a. Is about the size of the human genome
b. Is about the size of the yeast genome
c. Is somewhere between the sizes of the yeast and human genomes
d. Cannot be predicted with any certainty

Verified step by step guidance
1
Understand the context: The problem is asking about the predicted genome size of an amoeba, a single-celled organism, in comparison to the human genome and the yeast genome.
Consider the nature of genome sizes: Genome size can vary significantly among organisms, even those that are similar in terms of being single-celled or multicellular.
Evaluate the options: The problem provides four options regarding the amoeba's genome size relative to the human and yeast genomes.
Recognize the variability in genome sizes: Genome size does not necessarily correlate with the complexity or type of organism. Amoebas, despite being single-celled, can have large genomes.
Conclude based on biological principles: Given the variability and lack of direct correlation between organism type and genome size, the genome size of an amoeba cannot be predicted with certainty based solely on the genome sizes of humans and yeast.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Genome Size Variation

Genome size refers to the total number of base pairs in an organism's DNA. It varies significantly across different species, and does not necessarily correlate with organism complexity. For example, some single-celled organisms can have larger genomes than multicellular ones, highlighting the unpredictability of genome size based solely on organism type.
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C-value Paradox

The C-value paradox describes the lack of correlation between genome size and organismal complexity. Despite expectations, more complex organisms do not always have larger genomes. This paradox is due to non-coding DNA and repetitive sequences that contribute to genome size without increasing complexity, making predictions about genome size challenging.
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Amoeba Genome Size

Amoebas, despite being single-celled organisms, can have extremely large genomes, sometimes exceeding those of humans. This is due to the presence of large amounts of non-coding DNA and repetitive sequences. Therefore, predicting the genome size of an amoeba based on other single-celled organisms like yeast is unreliable, as amoebas can have much larger genomes.
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Related Practice
Textbook Question
What do restriction endonucleases do?
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Textbook Question

What is a plasmid?

a. An organelle found in many bacteria and certain eukaryotes

b. A circular DNA molecule that replicates independently of the main chromosome(s)

c. A type of virus that has a DNA genome and infects certain types of human cells, including lung and respiratory tract tissue

d. A type of virus that has an RNA genome, codes for reverse transcriptase, and inserts a cDNA copy of its genome into cells

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Textbook Question

After finding a gene that causes a disease, researchers often introduce the defective allele into mice to create an animal model of the disease. Why are these models valuable?

a. They allow the testing of potential drug therapies without endangering human patients.

b. They allow the sequencing of the mutant allele.

c. They allow the production of large quantities of the defective gene product, usually a protein.

d. They allow the study of how the gene was transmitted from parents to offspring.

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Textbook Question

Explain how RNA-seq can be used to analyze patterns of gene expression.

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Textbook Question

Consider the validity of the following statements about genome editing. Select True or False for each statement.

T/FCas proteins work as endonucleases.

T/FsgRNA is used by bacterial cells to detect which DNA to cut.

T/FHomologous recombination is always used to join pieces of broken DNA.

T/FIt is possible to modify genes as well as disrupt them by genome editing.

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Textbook Question

Gene density is the number of genes per million base pairs (Mbp). Using Figure 20.5b, find the approximate number of genes estimated in water fleas and in humans, and note the size of each genome. Calculate the gene density in water fleas relative to that in humans.

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