Design a brief reasoning chain that explains why humans require more water by mass than macronutrients, and choose the option that best matches that logical sequence.

• A. Water contains more caloric energy per gram than fats, carbohydrates, and proteins, and therefore must be consumed in large amounts to meet high daily energy requirements
• B. Water is the primary structural polymer of cells akin to proteins and must be synthesized from dietary fibers in large amounts to maintain cell structure
• C. Humans evolved to use water as a micronutrient stored in adipose tissue and therefore daily intake replaces this long-term storage
• D. Water participates as medium in all cellular reactions, constitutes a large fraction of body mass, is lost continually via excretion and evaporation, and cannot be stored long-term like fat, hence intake must be greater

Answer: (D)