What is the correct sequence of events in the duodenum immediately after acidic chyme enters from the stomach to prepare nutrients for absorption?

• A. Pancreatic proteases first polymerize amino acids into larger proteins to slow absorption, after which bile salts deactivate carbohydrates so they pass unabsorbed to the large intestine for fermentation.
• B. Chyme bypasses the duodenum entirely and is immediately exposed to brush border enzymes in the ileum which neutralize acid and emulsify fats before any pancreatic contribution occurs.
• C. Bile is secreted directly into enterocytes to chemically convert proteins to glucose, followed by pancreatic acidification that preserves enzyme structure for absorption in the colon.
• D. Pancreatic bicarbonate neutralizes acid → bile emulsifies lipids → pancreatic enzymes (amylase, lipase, proteases) perform hydrolysis → resulting small molecules packaged for absorption.

Answer: (D)