Design a brief clinical monitoring plan (choose the best option) for a patient who took excessive vitamin A supplements for months and now stopped; which monitoring elements prioritize safety and why?

• A. Immediately administer high-dose vitamin K and vitamin E to accelerate hepatic clearance of vitamin A and stop monitoring because co‑administration will correct toxicity within 24 hours.
• B. Only check serum 25‑OH vitamin D and bone mineral density, since vitamin A excess primarily affects bone density and vitamin D status will normalize hepatic vitamin A overload immediately.
• C. No monitoring is needed; once supplements are stopped, fat-soluble vitamin levels always normalize within 48 hours due to rapid redistribution into adipose stores.
• D. Monitor hepatic function tests and serum retinol periodically, assess for signs of chronic hypervitaminosis A (headache, hepatomegaly), counsel gradual taper if symptoms persist—because vitamin A is stored in liver and toxicity can be prolonged after discontinuation.

Answer: (D)