D-Talose, a constituent of certain antibiotics, has the open-chain structure shown next. Draw d-talose in its cyclic hemiacetal form.

Question

Open-chain structure of D-Talose, a monosaccharide, with labeled hydroxyl and hydrogen groups.

Accepted Answer

Hello everyone today. With the following problem. D glucose is a monocycle. I found in many fruits, draw D glucose in its cyclic he acetyl form, both alpha and beta animals. So we will first draw the alpha, an animal and then later get the beta anma from that. So first, you wanna number the carbons starting with one at the aldehyde group. And then we want to rotate this molecule, this D glucose 90 degrees clockwise such that we have uh following. So we will just number this from here. We want to coil carbons five and six clockwise such that it forms sort of a ring. So we have uh this structure and then we want to rotate carbon five such that the primary alcohol group faces up. So we will rotate carbon five such that we have at the resulting structure. No, to complete the civilization. The hydroxyl group with the alcohol group of carbon five will attack or perform nucleic addition to the carbon of the aldehyde. Such that we will have formed our alpha. And for alpha animals, the hydroxy group on carbon one will point down and that is the anim American carbon to be more specific. So the hydroxy group on carbon one will point down as for the hydroxy groups on the rest of the carbons, they are in their specific locations. Due to, for example, carbon two in the fissure projection was the hydroxy group is to the right. So in the ring, it will point down on carbon three, the hydroxyl group and the fissure projection was to the left. So it points up in the ring and then carbon four follows the same rule as carbon two. So we have our alpha and to draw the beta ener, we simply just switch the orientation of the hydroxyl group on carbon one such that the hydroxy group is pointing up. And with that, we have solved the problem. Overall, I helped us, helped Hansel next time.

D-Talose, a constituent of certain antibiotics, has the open-chain structure shown next. Draw d-talose in its cyclic hemiacetal form.

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Key Concepts

Hemiacetal Formation

Cyclic Sugar Structures

Anomeric Carbon