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Clinical Laboratory Hematology, 4th edition

Published by Pearson (March 15, 2019) © 2020

  • Shirlyn B. McKenzie University of Texas Health Science Center at San Antonio
  • Kristin Landis-Piwowar
  • Lynne Williams

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For courses in hematology and coagulation.

Building a solid foundation in laboratory hematology, for both MLT and MLS students

Clinical Laboratory Hematology is a comprehensive survey of laboratory hematology balancing theory with practical applications. It's perfect for students at all levels of an MLT/MLS program. The text combines detailed technical information with a running case study. This format helps students synthesize and analyze information, answer questions and solve problems, and consider real-world implications.

The 4th Edition has been thoroughly updated with the latest advances in laboratory medicine. It has new engaging features, including a new interactive library of nearly 1,200 images.

Hallmark features of this title

Solid foundation in clinical laboratory hematology

  • Comprehensive information on normal hematopoiesis and cell processes gives students a solid foundation in the pathophysiology of hematologic/hemostatic diseases.
  • Algorithms for critical pathways and reflex testing pathways illustrate effective, cost-efficient uses of laboratory tests in diagnosis or treatment planning.

Organizational and learning aids

  • Objectives are divided into two levels: Level I (basic) and Level II (advanced). Objectives are associated with chapter modules.
  • A running case study is referenced throughout the chapter. It provides clinical and lab information pertinent to the chapter content.
  • Case study questions and checkpoints gauge students' grasp of concepts from a module.

New and updated features of this title

Significant content updates

  • UPDATED: Chapter 12, Anemias of Disordered Regulation of Iron Metabolism and Heme Synthesis, has significant updates related to iron metabolism.
  • UPDATED: Chapter 25, Myelodysplastic Syndromes, has been extensively updated.
  • UPDATED: Two types of WHO 2017 classifications are now reflected in Appendices B and C. The two classifications are (1) hematopoietic and lymphoid tissue, and (2) hematopoietic, lymphopoietic, and histiocytic/dendritic neoplasms.

Engaging pedagogy

  • EXPANDED: Extra multiple-choice questions have been added for each objective level (basic and advanced).
  • NEW: Figures and tables that previously appeared in online student resources have now been incorporated into the chapters.
  • EXPANDED: New and updated microphotographs appear in the new edition. Microphotographs are displayed liberally throughout and are typical of those found of a particular disease or disorder.
  • NEW: An image atlas is new to this edition. It is an interactive library of nearly 1,200 images.

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SECTION 1

  1. Introduction
  2. Cellular Homeostasis
  3. Structure and Function of Hematopoietic Organs

SECTION 2

  1. Hematopoiesis
  2. The Erythrocyte
  3. Hemoglobin
  4. Granulocytes and Monocytes
  5. Lymphocytes
  6. The Platelet
  7. The Complete Blood Count and Peripheral Blood Smear Evaluation
  8. Introduction to Anemia

SECTION 3

  1. Anemias of Disordered Regulation of Iron Metabolism and Heme Synthesis
  2. Hemoglobinopathies: Qualitative Defects
  3. Thalassemia
  4. Megaloblastic and Nonmegaloblastic Macrocytic Anemias
  5. Hypoproliferative Anemias
  6. Hemolytic Anemia: Membrane Defects
  7. Hemolytic Anemia: Enzyme Deficiencies
  8. Hemolytic Anemia: Immune Anemias
  9. Hemolytic Anemia: Nonimmune Defects
  10. Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes
  11. Nonmalignant Lymphocyte Disorders
  12. Introduction to Hematopoietic Neoplasms
  13. Myeloproliferative Neoplasms
  14. Myelodysplastic Syndromes
  15. Acute Myeloid Leukemias
  16. Precursor Lymphoid Neoplasms
  17. Mature Lymphoid Neoplasms
  18. Hematopoietic Stem Cell Transplantation
  19. Morphologic Analysis of Body Fluids in the Hematology Laboratory
  20. Primary Hemostasis
  21. Secondary Hemostasis and Fibrinolysis
  22. Disorders of Primary Hemostasis
  23. Disorders of Secondary Hemostasis
  24. Thrombophilia
  25. Hemostasis: Laboratory Testing and Instrumentation
  26. Hematology Procedures
  27. Bone Marrow Examination
  28. Automation in Hematology
  29. Flow Cytometry
  30. Chromosome Analysis of Hematopoietic and Lymphoid Disorders
  31. Molecular Analysis of Hematologic Diseases
  32. Quality Assessment in the Hematology Laboratory

Appendices

  1. Reference Intervals
  2. Hematopoietic Neoplasms
  3. WHO 2017 Classifications
  4. Hematology Procedures
  5. Chapter Quiz Answer Key
  6. Checkpoints Answer Key
  7. Case Study Answer Key

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