Skip to main content
Pearson+ LogoPearson+ Logo
Ch. 11 How Genes Are Controlled
Taylor - Campbell Biology: Concepts & Connections 10th Edition
Taylor, Simon, Dickey, Hogan10th EditionCampbell Biology: Concepts & ConnectionsISBN: 9780136538783Not the one you use?Change textbook
Chapter 11, Problem 7

All your cells contain proto-oncogenes, which can change into cancer-causing oncogenes. Why do cells possess such potential time bombs?

Verified step by step guidance
1
Understand the role of proto-oncogenes: Proto-oncogenes are normal genes that play a crucial role in normal cell growth and division. They encode for proteins that help to regulate cell growth and differentiation.
Recognize the mutation process: Proto-oncogenes can become oncogenes through mutations, which can be caused by various factors such as environmental exposure, radiation, and chemical carcinogens. These mutations may cause the proto-oncogene to be overactive.
Consider the balance of cell regulation: In a healthy cell, the balance between proto-oncogenes and tumor suppressor genes (which inhibit cell growth) ensures that cells grow and divide only when necessary. Disruption in this balance can lead to uncontrolled cell division and cancer.
Acknowledge evolutionary significance: The presence of proto-oncogenes is not merely a 'time bomb,' but rather a component of a highly regulated system that supports normal cellular function and organismal development. These genes have been conserved throughout evolution because of their essential roles.
Explore the research implications: Understanding how proto-oncogenes can become oncogenes contributes to cancer research, aiding in the development of targeted therapies that can specifically inhibit the overactive oncogenes without affecting the normal function of proto-oncogenes.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
1m
Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Proto-oncogenes

Proto-oncogenes are normal genes that play a crucial role in cell growth and division. They encode proteins that help regulate cell proliferation and differentiation. When mutated or abnormally expressed, these genes can become oncogenes, leading to uncontrolled cell growth and cancer. Understanding proto-oncogenes is essential for grasping how cancer can develop from normal cellular processes.
Recommended video:
Guided course
04:02
Types of Genes Regulating Cell Growth

Oncogenes

Oncogenes are mutated forms of proto-oncogenes that promote cancerous growth. They can result from various factors, including genetic mutations, environmental influences, or viral infections. Oncogenes lead to the overproduction of proteins that drive cell division and survival, bypassing the normal regulatory mechanisms. This transformation is a key step in the development of tumors and cancer.
Recommended video:
Guided course
04:02
Types of Genes Regulating Cell Growth

Cellular Regulation

Cellular regulation refers to the complex mechanisms that control cell growth, division, and death. This includes signaling pathways that respond to internal and external cues, ensuring that cells only divide when necessary. Disruptions in these regulatory processes can lead to the activation of oncogenes and the development of cancer. Understanding cellular regulation is vital for comprehending how proto-oncogenes can become potential threats to cellular integrity.
Recommended video:
Guided course
03:31
Cell Cycle Regulation
Related Practice
Textbook Question

Which of the following is a valid difference between embryonic stem cells and the stem cells found in adult tissues?

a. In laboratory culture, only adult stem cells are immortal.

b. In nature, only embryonic stem cells give rise to all the different types of cells in the organism.

c. Only adult stem cells can differentiate in culture.

d. Embryonic stem cells are generally more difficult to grow in culture than adult stem cells.

1520
views
Textbook Question

The control of gene expression is more complex in multicellular eukaryotes than in prokaryotes because __________. (Explain your answer.)

a. Eukaryotic cells are much smaller

b. In a multicellular eukaryote, different cells are specialized for different functions

c. Prokaryotes are restricted to stable environments

d. Eukaryotes have fewer genes, so each gene must do several jobs

951
views
Textbook Question

Your bone cells, muscle cells, and skin cells look different because

a. Each cell contains different kinds of genes.

b. They are present in different organs.

c. Different genes are active in each kind of cell.

d. They contain different numbers of genes.

1769
views
Textbook Question

You obtain an egg cell from the ovary of a white mouse and remove the nucleus from it. You then obtain a nucleus from a liver cell from an adult black mouse. You use the methods of nuclear transplantation to insert the nucleus into the empty egg. After some prompting, the new zygote divides into an early embryo, which you then implant into the uterus of a brown mouse. A few weeks later, a baby mouse is born. What color will it be? Why?

988
views
Textbook Question

Mutations can alter the function of the lac operon (see Module 11.1). Predict how the following mutations would affect the function of the operon in the presence and absence of lactose:

a. Mutation of the regulatory gene; repressor cannot bind to lactose.

b. Mutation of operator; repressor will not bind to operator.

c. Mutation of regulatory gene; repressor will not bind to operator.

d. Mutation of promoter; RNA polymerase will not attach to promoter.

2514
views
Textbook Question

It took three sheep to create the clone Dolly: A blackface sheep donated the egg, a whiteface sheep donated the mammary cells from which the nucleus was taken, and a blackface sheep served as surrogate. Assuming face color is genetically determined, what color face did Dolly have?

1408
views