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Ch. 11 How Genes Are Controlled
Taylor - Campbell Biology: Concepts & Connections 10th Edition
Taylor, Simon, Dickey, Hogan10th EditionCampbell Biology: Concepts & ConnectionsISBN: 9780136538783Not the one you use?Change textbook
Chapter 11, Problem 8

You obtain an egg cell from the ovary of a white mouse and remove the nucleus from it. You then obtain a nucleus from a liver cell from an adult black mouse. You use the methods of nuclear transplantation to insert the nucleus into the empty egg. After some prompting, the new zygote divides into an early embryo, which you then implant into the uterus of a brown mouse. A few weeks later, a baby mouse is born. What color will it be? Why?

Verified step by step guidance
1
Understand the concept of nuclear transplantation: In this process, the nucleus of one cell is removed and replaced with the nucleus of another cell. The genetic material (DNA) in the nucleus determines the traits of the organism.
Identify the source of the nucleus: The nucleus used in this case comes from a liver cell of an adult black mouse. This nucleus contains the complete genetic information (genome) of the black mouse.
Recognize the role of the egg cell: The egg cell from the white mouse has had its nucleus removed, meaning it no longer contains its own genetic material. It only provides the cytoplasm and cellular machinery necessary for development.
Understand the role of the surrogate mother: The brown mouse serves as the host for the embryo, providing the environment for the embryo to develop, but it does not contribute any genetic material to the offspring.
Conclude the offspring's traits: Since the genetic material in the nucleus determines the traits of the organism, and the nucleus came from the black mouse, the baby mouse will have the genetic traits of the black mouse, including its black fur color.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Nuclear Transplantation

Nuclear transplantation is a technique where the nucleus of a donor cell is transferred into an enucleated egg cell. This process allows the egg to develop into an embryo using the genetic material from the donor nucleus. In this scenario, the nucleus from a liver cell of a black mouse is inserted into the egg cell of a white mouse, which is crucial for understanding the genetic outcome of the resulting organism.
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Genetic Expression and Phenotype

The phenotype of an organism, such as its color, is determined by the expression of genes inherited from its parents. In this case, the baby mouse will express the traits associated with the black mouse's liver cell nucleus, as the genetic information from the nucleus dictates the development of the organism. Thus, the color of the baby mouse will reflect the genetic traits of the black mouse.
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Genotype & Phenotype

Mitochondrial DNA and Maternal Influence

While the nucleus contains the majority of genetic information, the egg cell also contributes mitochondrial DNA, which is inherited maternally. However, in this scenario, the phenotype is primarily influenced by the nuclear DNA from the black mouse. The maternal influence from the white mouse's egg is less significant in determining the color of the offspring, as the dominant traits from the black mouse's nucleus will prevail.
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Mitochondria Structure
Related Practice
Textbook Question

The control of gene expression is more complex in multicellular eukaryotes than in prokaryotes because __________. (Explain your answer.)

a. Eukaryotic cells are much smaller

b. In a multicellular eukaryote, different cells are specialized for different functions

c. Prokaryotes are restricted to stable environments

d. Eukaryotes have fewer genes, so each gene must do several jobs

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Textbook Question

Your bone cells, muscle cells, and skin cells look different because

a. Each cell contains different kinds of genes.

b. They are present in different organs.

c. Different genes are active in each kind of cell.

d. They contain different numbers of genes.

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Textbook Question

All your cells contain proto-oncogenes, which can change into cancer-causing oncogenes. Why do cells possess such potential time bombs?

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Textbook Question

Mutations can alter the function of the lac operon (see Module 11.1). Predict how the following mutations would affect the function of the operon in the presence and absence of lactose:

a. Mutation of the regulatory gene; repressor cannot bind to lactose.

b. Mutation of operator; repressor will not bind to operator.

c. Mutation of regulatory gene; repressor will not bind to operator.

d. Mutation of promoter; RNA polymerase will not attach to promoter.

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Textbook Question

It took three sheep to create the clone Dolly: A blackface sheep donated the egg, a whiteface sheep donated the mammary cells from which the nucleus was taken, and a blackface sheep served as surrogate. Assuming face color is genetically determined, what color face did Dolly have?

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Textbook Question

The success of an experiment often depends on choosing an appropriate organism to study. For example, Gregor Mendel was able to deduce the fundamental principles in genetics in part because of his choice of the pea plant. Reviewing Module 10.1, how did Hershey and Chase take advantage of the unique structural properties of bacteriophage T2 to determine the genetic material?

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