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Ch.12 Food as Fuel An Overview of Metabolism
Frost - General, Organic and Biological Chemistry 4th Edition
Frost4th EditionGeneral, Organic and Biological ChemistryISBN: 9780134988696Not the one you use?Change textbook
Chapter 8, Problem 90

Name the reaction that removes nitrogen from an α-amino acid, forming an α-keto acid.

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1
Identify the type of reaction that involves the removal of an amino group from an α-amino acid.
Recognize that this reaction typically involves the conversion of the amino group into a keto group.
Understand that the process of removing an amino group from an amino acid is known as deamination.
Note that when the amino group is removed and replaced by a keto group, the reaction is specifically called transamination.
Conclude that the reaction that removes nitrogen from an α-amino acid, forming an α-keto acid, is known as transamination.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Transamination

Transamination is a biochemical process where an amino group from an α-amino acid is transferred to an α-keto acid, resulting in the formation of a new α-amino acid and a new α-keto acid. This reaction is crucial in amino acid metabolism and allows for the interconversion of amino acids, facilitating the removal of nitrogen.
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Amino Acid Catabolism: Amino Group Example 2

Deamination

Deamination is the process of removing an amino group from an amino acid, leading to the formation of an α-keto acid and ammonia. This reaction is essential for the catabolism of amino acids, allowing the body to utilize the carbon skeleton for energy production while excreting nitrogenous waste.
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Review of Metabolism Example 1

α-Keto Acid

An α-keto acid is a type of organic acid that contains a keto group (C=O) adjacent to a carboxylic acid group. These compounds play a significant role in metabolism, serving as intermediates in various biochemical pathways, including the citric acid cycle and amino acid synthesis.
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