One strategy used in many different biochemical pathways is an initial investment of energy early on and a large payoff in energy at the end of the pathway. How is this strategy utilized in the catabolism of fats?

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Hi, everybody. Let's take a look at our next question. A strategy that is employed in a variety of bio comical pathways involves investing energy early on and reaping a large energy payoff at the end. Which of the following statements demonstrates its application in fat catabolism. A, the formation of glycerol occurs simultaneously with the conversion of A TP to A MP and pyrophosphate. This energy expenditure is recovered through lipogenesis. B the breakdown of fatty acids activates the conversion of to ATP and pyrophosphate. This provides energy for the hydrolysis of tri ayl glycerol. To see the formation of A fatty AC L coa occurs simultaneously with the conversion of A TP to A MP and pyrophosphate. This energy expenditure is recovered through the beta oxidation of fatty acids and d the breakdown of triglycerides activates the conversion of A MP to A TP and pyrophosphate. This provides energy for the storage of fatty acids. So in fat catabolism, the energy expenditure occurs in the activation step and that involves a conversion of the fatty acid into a fatty AC LC A. So the addition of the coenzyme A to the fatty acid and this requires energy expenditure which is provided by a TP. So a TP is used strangely enough becomes a MP I say strangely because we're used to seeing conversion of a TP into AD P. So this actually utilizes two high energy phosphate bonds. So when we look at our answer choices, this corresponds with choice C the formation of a fatty aya occurs simultaneously with the conversion of A TP to AM PM pyre phosphate. This energy expenditure is recovered through the beta oxidation of fatty acids. So then we'll go on with further steps in the beta oxidation process that is going to yield energy to make up for this initial energy expenditure. So choice C is going to be our answer. Choice A is incorrect because it's not glycerol that's formed. It's the fattier silo A and it says this energy expenditure is recovered through lipogenesis. But lipogenesis look at that genesis would involve the synthesis of lipids, not the breakdown. Then choice B has the A TP reaction backwards. So it says the breakdown of fatty acids A activates the conversion of A MP to A TP says this provides energy for the hydrolysis of tri ayl glycerol. But recall, we're supposed to be talking about an initial step that uses up a lot of energy and then finally choice D and then twist T is incorrect because it says the breakdown of triglycerides, triglycerides activates the conversion of A MP to A TP. So it has a TP going in the wrong direction. And instead of activation by synthesizing fatty acyl coa is talking about breakdown of triglycerides. Then it says this provides energy for the storage of fatty acids, but we're not storing them, we're breaking them down. So again, our strategy for investing energy early on in fat catabolism to yield energy later is described by choice C. The formation of a fatty acyl coa occurs simultaneously with the conversion of A TP to A MP and Fyr phosphate. This energy expenditure is recovered through the beta oxidation of fatty acids. See you in the next video.

One strategy used in many different biochemical pathways is an initial investment of energy early on and a large payoff in energy at the end of the pathway. How is this strategy utilized in the catabolism of fats?

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Key Concepts

Catabolism

Energy Investment Phase

Beta-Oxidation