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Ch. 4 - Gene Interaction
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 4, Problem 14

Flower color in snapdragons results from the amount of the pigment anthocyanin in the petals. Red flowers are produced by plants that have full anthocyanin production, and ivory-colored flowers are produced by plants that lack the ability to produce anthocyanin. The allele An1 has full activity in anthocyanin production, and the allele An2 is a null allele. Dr. Ara B. Dopsis, a famous genetic researcher, crosses pure-breeding red snapdragons to pure-breeding ivory snapdragons and produces F₁ progeny plants that have pink flowers. He proposes that this outcome is the result of incomplete dominance, and he crosses the F₁ to test his hypothesis. What phenotypes does Dr. Dopsis predict will be found in the F₂, and in what proportions?

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1
Identify the genotypes of the parent plants: Pure-breeding red snapdragons have the genotype An1An1, and pure-breeding ivory snapdragons have the genotype An2An2.
Determine the genotype of the F₁ progeny: Since the F₁ progeny are the result of crossing An1An1 with An2An2, they will all have the genotype An1An2.
Understand the concept of incomplete dominance: In incomplete dominance, the heterozygous phenotype (An1An2) is intermediate between the two homozygous phenotypes (An1An1 and An2An2), resulting in pink flowers.
Predict the genotypes of the F₂ generation: Cross the F₁ plants (An1An2) with each other to produce the F₂ generation. The possible genotypes are An1An1, An1An2, and An2An2.
Determine the phenotypic ratios in the F₂ generation: An1An1 will produce red flowers, An1An2 will produce pink flowers, and An2An2 will produce ivory flowers. Calculate the expected proportions based on Mendelian inheritance.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Incomplete Dominance

Incomplete dominance is a genetic phenomenon where the phenotype of heterozygous individuals is intermediate between the phenotypes of the two homozygous parents. In the case of snapdragons, crossing red (full anthocyanin) and ivory (no anthocyanin) results in pink flowers, demonstrating that neither allele is completely dominant over the other. This concept is crucial for predicting the phenotypic ratios in the offspring of subsequent generations.
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Alleles and Their Functions

Alleles are different forms of a gene that can exist at a specific locus on a chromosome. In this scenario, the An1 allele allows for full anthocyanin production, while the An2 allele is a null allele that does not produce anthocyanin. Understanding the function of these alleles is essential for predicting the phenotypes of the F₂ generation based on the genetic makeup of the F₁ progeny.
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Punnett Square and Phenotypic Ratios

A Punnett square is a tool used in genetics to predict the genotypes and phenotypes of offspring from a genetic cross. By crossing the F₁ pink snapdragons (An1An2) with each other, one can determine the expected phenotypic ratios in the F₂ generation. For this cross, the predicted phenotypic ratio will be 1 red: 2 pink: 1 ivory, illustrating the outcomes of incomplete dominance and the segregation of alleles.
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Related Practice
Textbook Question

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:

27/64 brown : 16/64 albino : 9/64 yellow : 9/64 black : 3/64 cream

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Textbook Question

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:

3/4 brown : 1/4 yellow

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Textbook Question

Total cholesterol in blood is reported as the number of milligrams (mg) of cholesterol per 100 milliliters (mL) of blood. The normal range is 180–220 mg/100 mL. A gene mutation altering the function of cell-surface cholesterol receptors restricts the ability of cells to collect cholesterol from blood and draw it into cells. This defect results in elevated blood cholesterol levels. Individuals who are heterozygous for a mutant allele and a wild-type allele have levels of 300–600 mg/100 mL, and those who are homozygous for the mutation have levels of 800–1000 mg/100 mL. Identify the genetic term that best describes the inheritance of this form of elevated cholesterol level, and justify your choice.

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Textbook Question

A plant line with reduced fertility comes to the attention of a plant breeder who observes that seed pods often contain a mixture of viable seeds that can be planted to produce new plants and withered seeds that cannot be sprouted. The breeder examines numerous seed pods in the reduced fertility line and counts 622 viable seeds and 204 nonviable seeds.

What single-gene mechanism best explains the breeder's observation?

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Textbook Question

A plant line with reduced fertility comes to the attention of a plant breeder who observes that seed pods often contain a mixture of viable seeds that can be planted to produce new plants and withered seeds that cannot be sprouted. The breeder examines numerous seed pods in the reduced fertility line and counts 622 viable seeds and 204 nonviable seeds.

Propose an additional experiment to test the genetic mechanism you propose. If your hypothesis is correct, what experimental outcome do you predict?

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Textbook Question

In cattle, an autosomal mutation called Dexter produces calves with short stature and short limbs. Embryos that are homozygous for the Dexter mutation have severely stunted development and either spontaneously abort or are stillborn. What progeny phenotypes do you expect from the cross of two Dexter cows? What are the expected proportions of the expected phenotypes?

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