Skip to main content
Pearson+ LogoPearson+ Logo
Ch. 4 - Gene Interaction
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 4, Problem 12c

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:
27/64 brown : 16/64 albino : 9/64 yellow : 9/64 black : 3/64 cream

Verified step by step guidance
1
Analyze the phenotypic ratio of the progeny (27:16:9:9:3) and compare it to known Mendelian inheritance patterns. This suggests a dihybrid cross involving two genes with epistasis.
Assign symbols to the genes involved. For example, let Gene A control pigment production (A = pigment, a = no pigment) and Gene B control pigment color (B = brown, b = yellow). Albino phenotype occurs when Gene A is homozygous recessive (aa), masking the effect of Gene B.
Determine the genotypes responsible for each phenotype: Brown (A-B-), Albino (aa--), Yellow (A-bb), Black (A-Bb), and Cream (AAbb). The phenotypic ratios align with these genotypes under a dihybrid cross with epistasis.
Identify the parental genotypes that could produce the observed progeny ratios. A likely combination is AaBb x AaBb, as this would produce the expected 9:3:3:1 ratio modified by epistasis to match the observed 27:16:9:9:3 ratio.
Verify the hypothesis by constructing a Punnett square for the cross AaBb x AaBb, considering the epistatic interaction between the two genes. Check that the resulting genotypic and phenotypic ratios align with the observed progeny distribution.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
1m
Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Genotype

Genotype refers to the genetic constitution of an organism, specifically the alleles it possesses for a particular trait. In this context, understanding the genotype is crucial for predicting the phenotypic ratios of the progeny. The genotype can be homozygous (two identical alleles) or heterozygous (two different alleles), and it directly influences the observable traits in the offspring.
Recommended video:
Guided course
07:52
Gamete Genotypes

Phenotype

Phenotype is the observable physical or biochemical characteristics of an organism, determined by both its genotype and environmental factors. In this question, the phenotypic ratios of the progeny (brown, albino, yellow, black, and cream) provide insight into the genetic makeup of the parents. Analyzing these ratios helps in deducing the possible genotypes that could lead to such offspring.
Recommended video:
Guided course
10:48
Mutations and Phenotypes

Punnett Square

A Punnett Square is a diagram used to predict the genetic outcomes of a cross between two organisms. It allows for the visualization of how alleles from each parent combine to form the genotypes of the offspring. By setting up a Punnett Square with the potential genotypes of the parents, one can calculate the expected phenotypic ratios, which is essential for solving the given problem.
Recommended video:
Guided course
18:27
Chi Square Analysis
Related Practice
Textbook Question

In the rats identified in Problem 10, a third independently assorting gene involved in the determination of coat color is the C gene. At this locus, the genotype C– permits expression of pigment from genes B and D. The cc genotype, however, prevents expression of coat color and results in albino rats. For each of the following crosses, determine the expected phenotype ratio of progeny.

BbDdCC×BbDdCC

418
views
Textbook Question

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:

9/16 brown : 3/16 black : 4/16 albino

572
views
Textbook Question

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:

3/8 black : 3/8 cream : 2/8 albino

703
views
Textbook Question

Using the information provided in Problems 10 and 11, determine the genotype and phenotype of parents that produce the following progeny:

3/4 brown : 1/4 yellow

566
views
Textbook Question

Total cholesterol in blood is reported as the number of milligrams (mg) of cholesterol per 100 milliliters (mL) of blood. The normal range is 180–220 mg/100 mL. A gene mutation altering the function of cell-surface cholesterol receptors restricts the ability of cells to collect cholesterol from blood and draw it into cells. This defect results in elevated blood cholesterol levels. Individuals who are heterozygous for a mutant allele and a wild-type allele have levels of 300–600 mg/100 mL, and those who are homozygous for the mutation have levels of 800–1000 mg/100 mL. Identify the genetic term that best describes the inheritance of this form of elevated cholesterol level, and justify your choice.

703
views
Textbook Question

Flower color in snapdragons results from the amount of the pigment anthocyanin in the petals. Red flowers are produced by plants that have full anthocyanin production, and ivory-colored flowers are produced by plants that lack the ability to produce anthocyanin. The allele An1 has full activity in anthocyanin production, and the allele An2 is a null allele. Dr. Ara B. Dopsis, a famous genetic researcher, crosses pure-breeding red snapdragons to pure-breeding ivory snapdragons and produces F₁ progeny plants that have pink flowers. He proposes that this outcome is the result of incomplete dominance, and he crosses the F₁ to test his hypothesis. What phenotypes does Dr. Dopsis predict will be found in the F₂, and in what proportions?

451
views