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Ch. 5 - Genetic Linkage and Mapping in Eukaryotes
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 5, Problem 2b

In a diploid species of plant, the genes for plant height and fruit shape are syntenic and separated by 18 m.u. Allele D produces tall plants and is dominant to d for short plants, and allele R produces round fruit and is dominant to r for oval fruit.


Give the same information for a plant with the genotype Dr/dR.

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Understand the problem: The question involves a diploid plant species with two syntenic genes (genes located on the same chromosome). The genes are separated by 18 map units (m.u.), which indicates a 18% recombination frequency. The alleles D and d control plant height, while R and r control fruit shape. The genotype Dr/dR represents the arrangement of alleles on homologous chromosomes.
Interpret the genotype Dr/dR: This notation indicates that one homologous chromosome carries the D allele for tall plants and the r allele for oval fruit, while the other homologous chromosome carries the d allele for short plants and the R allele for round fruit. This arrangement is referred to as a 'repulsion' or 'trans' configuration because the dominant alleles (D and R) are on different chromosomes.
Determine the parental and recombinant gametes: Since the genes are syntenic and separated by 18 m.u., the parental gametes (Dr and dR) will be more frequent, while the recombinant gametes (DR and dr) will occur less frequently. The recombination frequency of 18% means that 18% of the gametes will be recombinant, and the remaining 82% will be parental.
Calculate the expected proportions of gametes: To determine the proportions of each type of gamete, divide the recombination frequency equally between the two recombinant gametes (DR and dr). Similarly, divide the remaining frequency equally between the two parental gametes (Dr and dR). For example, if 18% are recombinant, then 9% will be DR and 9% will be dr, while 41% will be Dr and 41% will be dR.
Summarize the information: The plant with the genotype Dr/dR will produce four types of gametes: Dr, dR, DR, and dr. The parental gametes (Dr and dR) will be more frequent, while the recombinant gametes (DR and dr) will be less frequent. The exact proportions depend on the recombination frequency of 18%.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Synteny

Synteny refers to the conservation of gene order on chromosomes across different species or within a species. In this context, it indicates that the genes for plant height and fruit shape are located on the same chromosome and maintain their relative positions, which can affect inheritance patterns and genetic linkage.
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Genotype and Alleles

A genotype is the genetic constitution of an organism, represented by the alleles it possesses for specific traits. In the given example, 'Dr/dR' indicates that the plant has one allele for tall plants (D) and one for short plants (d), as well as one allele for round fruit (R) and one for oval fruit (r), showcasing the concept of heterozygosity.
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Map Units (m.u.)

Map units (m.u.) are a unit of measurement used in genetics to express the distance between genes on a chromosome, based on the frequency of recombination during meiosis. An 18 m.u. separation suggests that there is an 18% chance of recombination occurring between the genes for height and fruit shape, which influences the inheritance patterns of these traits.
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Related Practice
Textbook Question

Give the information requested.


The gametes produced by an organism with the genotype Rt/rT

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Textbook Question

Give the information requested.


Progeny of the cross Rt/rT×rt/rt

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Textbook Question

In a diploid species of plant, the genes for plant height and fruit shape are syntenic and separated by 18 m.u. Allele D produces tall plants and is dominant to d for short plants, and allele R produces round fruit and is dominant to r for oval fruit.


A plant with the genotype DR/dr produces gametes. Identify gamete genotypes, label parental and recombinant gametes, and give the frequency of each gamete genotype.

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Textbook Question

A pure-breeding tall plant producing oval fruit as described in Problem 2 is crossed to a pure-breeding short plant producing round fruit.


The F₁ are crossed to short plants producing oval fruit. What are the expected proportions of progeny phenotypes?

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Textbook Question

A pure-breeding tall plant producing oval fruit as described in Problem 2 is crossed to a pure-breeding short plant producing round fruit.


If the F₁ identified in part (a) are crossed to one another, what proportion of the F₂ are expected to be short and produce round fruit? What proportion are expected to be tall and produce round fruit?

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Textbook Question

Genes E and H are syntenic in an experimental organism with the genotype EH/eh. Assume that during each meiosis, one crossover occurs between these genes. No homologous chromosomes escape crossover, and none undergo double crossover. Are genes E and H genetically linked? Why or why not? What is the proportion of parental gametes produced by meiosis?

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