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Ch.12 Food as Fuel An Overview of Metabolism
Frost - General, Organic and Biological Chemistry 4th Edition
Frost4th EditionGeneral, Organic and Biological ChemistryISBN: 9780134988696Not the one you use?Change textbook
Chapter 8, Problem 83a

Identify the following as the reduced or oxidized form:
a. NAD+

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1
Step 1: Understand the concepts of oxidation and reduction. Oxidation involves the loss of electrons, while reduction involves the gain of electrons. In biological systems, these processes often involve the transfer of hydrogen atoms.
Step 2: Recognize that NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme involved in redox reactions. It alternates between two forms: NAD⁺ (oxidized form) and NADH (reduced form).
Step 3: Recall that NAD⁺ lacks the additional hydrogen atom and electrons that are present in NADH. This indicates that NAD⁺ is the oxidized form.
Step 4: Confirm that NAD⁺ is ready to accept electrons and a hydrogen atom during a reduction reaction, converting it into NADH.
Step 5: Conclude that NAD⁺ is the oxidized form in this context, as it has not yet gained electrons or hydrogen atoms.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Redox Reactions

Redox reactions, short for reduction-oxidation reactions, involve the transfer of electrons between two substances. In these reactions, one substance is oxidized (loses electrons) while another is reduced (gains electrons). Understanding redox processes is crucial for analyzing biochemical pathways, such as cellular respiration and photosynthesis.
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NAD⁺ and NADH

NAD⁺ (Nicotinamide adenine dinucleotide) is a coenzyme that plays a vital role in metabolic processes. It exists in two forms: the oxidized form (NAD⁺) and the reduced form (NADH). NAD⁺ accepts electrons during metabolic reactions, becoming NADH, which is essential for energy production in cells.
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Oxidation State

The oxidation state refers to the degree of oxidation of an atom in a chemical compound, indicating how many electrons have been lost or gained. In the context of NAD⁺, its oxidation state is higher than that of NADH, as NAD⁺ is the form that has not yet accepted electrons. This concept is fundamental in determining the roles of different molecules in redox reactions.
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