Textbook Question
In eukaryotic DNA, where are you most likely to find histone protein H4?
489
views
Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
Not the one you use?Change textbookSelect a different textbook
Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
All textbooks
Sanders 3rd EditionCh. 10 - Eukaryotic Chromosome Abnormalities and Molecular OrganizationProblem 3d
Sanders 3rd EditionCh. 10 - Eukaryotic Chromosome Abnormalities and Molecular OrganizationProblem 3dChapter 10, Problem 3d
In eukaryotic DNA, how does the role of H1 differ from the role of H3 in chromatin formation?
Verified step by step guidance1
Understand the structure of chromatin: Chromatin is composed of DNA wrapped around histone proteins to form nucleosomes. Histones are categorized into core histones (H2A, H2B, H3, and H4) and linker histones (H1).
Learn the role of H3: H3 is one of the core histones that forms the nucleosome core. It interacts with H2A, H2B, and H4 to create the octameric structure around which DNA is wrapped. This helps compact the DNA into a basic chromatin unit.
Learn the role of H1: H1 is a linker histone that binds to the DNA entering and exiting the nucleosome. It stabilizes the higher-order chromatin structure by promoting the folding of nucleosomes into a more compact 30-nm fiber.
Compare the roles: While H3 is directly involved in forming the nucleosome core and organizing DNA at the fundamental level, H1 is responsible for higher-order chromatin compaction and regulating accessibility of DNA for processes like transcription.
Conclude the distinction: H3 is essential for the structural integrity of the nucleosome, whereas H1 plays a regulatory role in chromatin organization and gene expression by influencing the overall chromatin architecture.
Verified video answer for a similar problem:
This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
1mWas this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Histone Proteins
Histone proteins are essential components of chromatin, the structure that packages DNA in eukaryotic cells. They help organize DNA into nucleosomes, which are the fundamental units of chromatin. There are several types of histones, including H1, H2A, H2B, H3, and H4, each playing specific roles in DNA packaging and regulation.
Recommended video:
Guided course
05:05
Proteins
Nucleosome Structure
A nucleosome consists of a segment of DNA wrapped around a core of histone proteins, specifically two copies each of H2A, H2B, H3, and H4. This structure allows for the compaction of DNA, making it fit within the nucleus while also regulating access to the genetic material. H1, known as the linker histone, binds to the DNA between nucleosomes, stabilizing the overall chromatin structure.
Recommended video:
Guided course
07:10Chromosome Structure
Chromatin Compaction
Chromatin compaction refers to the process by which DNA and histone proteins are organized into a more condensed form, allowing for efficient storage and regulation of genetic information. H1 plays a crucial role in this process by facilitating the higher-order folding of chromatin, while H3 is involved in the core structure of nucleosomes, influencing gene expression and DNA accessibility.
Recommended video:
Guided course
04:35Chromatin
Related Practice
Textbook Question
In eukaryotic DNA, where are you most likely to find histone protein H1?
460
views
Textbook Question
In eukaryotic DNA, along a 6000-bp segment of DNA, approximately how many molecules of each kind of histone protein do you expect to find? Explain your answer.
582
views
Textbook Question
Describe the importance of light and dark G bands that appear along chromosomes.
520
views
Textbook Question
Human late prophase karyotypes have about 2000 visible G bands. The human genome contains approximately 22,000 genes. Consider the region 5p1.5 through the end of the short arm of chromosome 5, which is identified on the late prophase chromosome in Figure 10.5, and assume the entire region is deleted. Approximately how many genes will be lost as a result of the deletion?
417
views
Textbook Question
Consider synapsis in prophase I of meiosis for two plant species that each carries 36 chromosomes. Species A is diploid and species B is triploid. What characteristics of homologous chromosome synapsis can be used to distinguish these two species?
373
views