Human late prophase karyotypes have about 2000 visible G bands. The human genome contains approximately 22,000 genes. Consider the region 5p1.5 through the end of the short arm of chromosome 5, which is identified on the late prophase chromosome in Figure 10.5, and assume the entire region is deleted. Approximately how many genes will be lost as a result of the deletion?

Question

Accepted Answer

Hello, everyone and welcome to today's video. So an organism's genome contains approximately 20,000 genes. A researcher discovers a large interstitial deletion on chromosome four that removes approximately one third of the chromosome's length. So approximately how many genes are expected to be deleted in this region. Now, as answer choice, A, we have 1250 genes. As answer choice B, we have 2450 genes. As answer choice, C we have 6667 genes. And as answer choice D we have 5000 genes. So we're told that this genome is going to be 20,000 genes. And then we're told that one third of them are removed by this deletion. So all we have to do is multiply 10, 20,000 times one third to determine the amount of genes that are going to be removed by this mutation by this deletion, which in this case is going to be 667. This is going to be the result of our multiplication and the answer choice that corresponds to this number is going to be answer choice 6667 Genes. I really hope this video helped you and I hope to see you on the next one.

Verified video answer for a similar problem:

Key Concepts

Karyotype and G-banding

Human Genome and Gene Count

Chromosomal Deletion