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Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 14, Problem C.2a

A tumor is a growing mass of abnormal cells. Describe the difference between a benign tumor and a malignant tumor.

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Step 1: Understand the definition of a tumor as a mass of abnormal cells that grow uncontrollably.
Step 2: Define a benign tumor as a non-cancerous growth that typically grows slowly and does not spread to other parts of the body.
Step 3: Define a malignant tumor as a cancerous growth that can grow rapidly, invade nearby tissues, and has the potential to spread (metastasize) to distant parts of the body.
Step 4: Highlight that benign tumors are usually encapsulated and less likely to cause serious harm, whereas malignant tumors are invasive and can disrupt normal body functions.
Step 5: Summarize the key difference: benign tumors remain localized and are generally less dangerous, while malignant tumors are aggressive and can spread, making them more harmful.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Benign Tumor

A benign tumor is a non-cancerous growth of abnormal cells that remains localized and does not invade surrounding tissues or spread to other parts of the body. These tumors usually grow slowly and are often encapsulated, making them less harmful and easier to remove.
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Malignant Tumor

A malignant tumor is a cancerous growth characterized by uncontrolled cell division, invasion into nearby tissues, and the potential to metastasize, or spread, to distant organs. Malignant tumors are aggressive, can disrupt normal body functions, and often require more intensive treatment.
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Tumor Growth and Metastasis

Tumor growth involves abnormal cell proliferation, but only malignant tumors have the ability to metastasize, meaning cancer cells break away, travel through the bloodstream or lymphatic system, and form new tumors elsewhere. This process distinguishes malignant tumors from benign ones and impacts prognosis and treatment.
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Related Practice
Textbook Question

Go to the website http://www.cancer.gov and select 'Cancer Types' on the top menu bar. Scroll down to 'Breast Cancer' and click. Select 'Cases & Prevention' from the options. Click 'More information' and select 'BRCA Mutations: Cancer Risk and Genetic Testing'. Use the information on this page to answer the following questions. Are there measures a woman with a positive result can take to lessen her chances of developing cancer or to catch a cancer early in its development?

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Textbook Question

Based on what you read in this chapter, Can a tumor arise from a single mutated cell? Are all the cells in a tumor identical?

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Textbook Question

Why do most cancers require the mutation of multiple genes?

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Textbook Question

A tumor is a growing mass of abnormal cells. Give an example from this chapter of a benign tumor that becomes a malignant tumor.

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Textbook Question

A tumor is a growing mass of abnormal cells. What must happen for a benign tumor to become malignant?

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Textbook Question

Genetic counseling has not been discussed in this chapter, but it is a service provided by trained professional counselors who also have detailed knowledge of medical genetics, as described in Application Chapter A. Genetic counselors provide details about gene mutations and have knowledge of most of the details of diseases associated with genetic abnormalities. With regard to genetic testing to identify one's personal risk of cancer, what are the three or four topics you think are most important to be able to discuss with a genetic counselor?

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