Go to the website http://www.ncbi.nlm.nih.gov/omim and enter 'Lynch syndrome' in the Search box at the top of the page. From the list of options given, select '#120435—Lynch Syndrome.' Use the information you retrieve to answer the following questions. Provide a brief summary of the normal functions of the protein products of these genes.

Sanders 3rd Edition
Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics
Problem C.9dGo to the website http://www.cancer.gov and select 'Cancer Types' on the top menu bar. Scroll down to 'Breast Cancer' and click. Select 'Cases & Prevention' from the options. Click 'More information' and select 'BRCA Mutations: Cancer Risk and Genetic Testing'. Use the information on this page to answer the following questions. Are there measures a woman with a positive result can take to lessen her chances of developing cancer or to catch a cancer early in its development?
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Key Concepts
BRCA Gene Mutations and Cancer Risk
Preventive Measures for High-Risk Individuals
Early Detection and Screening Strategies
Go to the website http://www.ncbi.nlm.nih.gov/omim and enter 'Lynch syndrome' in the Search box at the top of the page. From the list of options given, select '#120435—Lynch Syndrome.' Use the information you retrieve to answer the following questions. What are the approximate rates of cancer that develop in people carrying a mutation of one of these genes?
Explain the following processes involving chromosome mutations and cancer development.
How the chromosome mutation producing Burkitt lymphoma generates the disease.
Based on what you read in this chapter, Can a tumor arise from a single mutated cell? Are all the cells in a tumor identical?
Why do most cancers require the mutation of multiple genes?
A tumor is a growing mass of abnormal cells. Describe the difference between a benign tumor and a malignant tumor.