Textbook Question
How many Barr bodies are found in a normal human female nucleus? In a normal male nucleus?
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Ch. 3 - Cell Division and Chromosome Heredity
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 3, Problem 11c
Describe the role of the following structures or proteins in cell division:
Kinetochores
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Understand that kinetochores are protein complexes located at the centromere of each chromosome. Their primary role is to facilitate the attachment of spindle microtubules during cell division.
Recognize that kinetochores are essential for ensuring accurate chromosome segregation. They act as a physical connection between the chromosomes and the spindle apparatus.
Learn that kinetochores generate tension by pulling on the microtubules, which helps align chromosomes at the metaphase plate during metaphase of mitosis or meiosis.
Explore how kinetochores play a role in the spindle assembly checkpoint, ensuring that all chromosomes are properly attached to the spindle before progressing to anaphase. This prevents errors in chromosome segregation.
Understand that during anaphase, kinetochores facilitate the movement of chromosomes toward opposite poles of the cell by interacting with depolymerizing microtubules, ensuring the proper distribution of genetic material.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Kinetochores
Kinetochores are protein complexes that assemble on the centromere of a chromosome during cell division. They serve as attachment points for spindle fibers, which are crucial for the movement of chromosomes. Kinetochores ensure that sister chromatids are pulled apart accurately during mitosis and meiosis, facilitating proper chromosome segregation.
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Mitosis Steps
Spindle Apparatus
The spindle apparatus is a structure composed of microtubules that orchestrates the separation of chromosomes during cell division. It forms during prophase and is responsible for aligning chromosomes at the metaphase plate and pulling them apart during anaphase. The proper functioning of the spindle apparatus is essential for maintaining genetic stability in daughter cells.
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Cell Division Phases
Cell division occurs in distinct phases: prophase, metaphase, anaphase, and telophase, collectively known as mitosis. Each phase has specific events, such as chromosome condensation, alignment, separation, and reformation of the nuclear envelope. Understanding these phases is crucial for comprehending how kinetochores and the spindle apparatus function to ensure accurate cell division.
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Related Practice
Textbook Question
Describe the role of the following structures or proteins in cell division:
Microtubules
546
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Textbook Question
Describe the role of the following structures or proteins in cell division:
Cohesin protein
500
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Textbook Question
Describe the role of the following structures or proteins in cell division:
Synaptonemal complex
448
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Textbook Question
A woman's father has ornithine transcarbamylase deficiency (OTD), an X-linked recessive disorder producing mental deterioration if not properly treated. The woman's mother is homozygous for the wild-type allele.
What is the woman's genotype? (Use D to represent the dominant allele and d to represent the recessive allele.)
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Textbook Question
A woman's father has ornithine transcarbamylase deficiency (OTD), an X-linked recessive disorder producing mental deterioration if not properly treated. The woman's mother is homozygous for the wild-type allele.
If the woman has a son with a man who does not have OTD, what is the chance the son will have OTD?
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