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Ch. 5 - Genetic Linkage and Mapping in Eukaryotes
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 5, Problem 27a

In tomatoes, the allele T for tall plant height is dominant to dwarf allele t, the P allele for smooth skin is dominant to the p allele for peach fuzz skin, and the allele R for round fruit is dominant to the recessive r allele for oblong fruit. The genes controlling these traits are linked on chromosome 1 in the tomato genome, and the genes are arranged in the order and with the recombination frequencies shown.
Gene arrangement and recombination frequencies for T, P, and R alleles in tomatoes.
A pure-breeding tall, peach fuzz, round plant is crossed to a pure-breeding plant that is dwarf, smooth, oblong. What are the gamete genotypes produced by each of these plants? 

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1
Step 1: Identify the parental genotypes. The pure-breeding tall, peach fuzz, round plant has the genotype TTPPRR, and the pure-breeding dwarf, smooth, oblong plant has the genotype ttpprr. These are homozygous for their respective alleles.
Step 2: Determine the arrangement of genes and recombination frequencies. The genes T, P, and R are linked on chromosome 1, with recombination frequencies of 0.04 between T and P, and 0.18 between P and R. This indicates that these genes are close together and recombination is less likely.
Step 3: Analyze the gametes produced by the pure-breeding tall, peach fuzz, round plant. Since this plant is homozygous dominant (TTPPRR), it will produce gametes with the genotype TPR, as no recombination occurs within homozygous alleles.
Step 4: Analyze the gametes produced by the pure-breeding dwarf, smooth, oblong plant. Since this plant is homozygous recessive (ttpprr), it will produce gametes with the genotype tpr, as no recombination occurs within homozygous alleles.
Step 5: Consider recombination possibilities for heterozygous offspring in future generations. If heterozygous offspring are produced, recombination between linked genes (T, P, R) will result in new combinations of alleles, with frequencies determined by the recombination rates (0.04 and 0.18).

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Dominant and Recessive Alleles

In genetics, alleles can be classified as dominant or recessive. A dominant allele, such as T for tall plant height, masks the effect of a recessive allele, like t for dwarf height. This means that if an organism has at least one dominant allele, the dominant trait will be expressed in the phenotype. Understanding this concept is crucial for predicting the traits of offspring in genetic crosses.
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Variations on Dominance

Linkage and Recombination

Linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together. The recombination frequency indicates how often crossing over occurs between linked genes during meiosis, affecting the genetic variation in gametes. In this case, the recombination frequencies for the genes T, P, and R help determine the likelihood of different allele combinations in the offspring.
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Gamete Formation

Gamete formation involves the process of meiosis, where diploid cells divide to produce haploid gametes. In this scenario, the pure-breeding tall, peach fuzz, round plant (TTPPRR) and the dwarf, smooth, oblong plant (ttpprr) will produce gametes with specific combinations of alleles. Understanding how to determine the gamete genotypes from the parental genotypes is essential for predicting the traits of the next generation.
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Related Practice
Textbook Question

The following progeny are obtained from a test cross of a trihybrid wild-type plant to a plant with the recessive phenotypes compound leaves (c), intercalary leaflets (i), and green fruits (g). (Traits not listed are wild type.) The test-cross progeny are as follows:

Determine the order of the three genes, and construct a genetic map that identifies the correct order and the alleles carried on each chromosome in the trihybrid parental plant.

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Textbook Question

The following progeny are obtained from a test cross of a trihybrid wild-type plant to a plant with the recessive phenotypes compound leaves (c), intercalary leaflets (i), and green fruits (g). (Traits not listed are wild type.) The test-cross progeny are as follows:

Calculate the frequencies of recombination between the adjacent genes in the map.

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Textbook Question

The following progeny are obtained from a test cross of a trihybrid wild-type plant to a plant with the recessive phenotypes compound leaves (c), intercalary leaflets (i), and green fruits (g). (Traits not listed are wild type.) The test-cross progeny are as follows:

How many double-crossover progeny are expected among the test-cross progeny? Calculate the interference for this cross.

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Textbook Question

In tomatoes, the allele T for tall plant height is dominant to dwarf allele t, the P allele for smooth skin is dominant to the p allele for peach fuzz skin, and the allele R for round fruit is dominant to the recessive r allele for oblong fruit. The genes controlling these traits are linked on chromosome 1 in the tomato genome, and the genes are arranged in the order and with the recombination frequencies shown.

What are the genotype and phenotype of the F₁ progeny of this cross?

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views
Textbook Question

In tomatoes, the allele T for tall plant height is dominant to dwarf allele t, the P allele for smooth skin is dominant to the p allele for peach fuzz skin, and the allele R for round fruit is dominant to the recessive r allele for oblong fruit. The genes controlling these traits are linked on chromosome 1 in the tomato genome, and the genes are arranged in the order and with the recombination frequencies shown.

What are the genotypes of gametes produced by the F₁, and what is the predicted frequency of each gamete?

456
views
Textbook Question

In tomatoes, the allele T for tall plant height is dominant to dwarf allele t, the P allele for smooth skin is dominant to the p allele for peach fuzz skin, and the allele R for round fruit is dominant to the recessive r allele for oblong fruit. The genes controlling these traits are linked on chromosome 1 in the tomato genome, and the genes are arranged in the order and with the recombination frequencies shown.

The F₁ are test-crossed to dwarf, peach fuzz, oblong plants, and 1000 test-cross progeny are produced. What are the phenotypes of test-cross progeny, and what number of progeny is expected in each class?

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