Suppose that base substitution mutations sufficient to eliminate the function of the operator regions listed below were to occur. For each case, describe how transcription or life cycle would be affected.
lacO mutation in E. coli

Question

lacO mutation in E. coli

Accepted Answer

Hey, everyone. Let's take a look at this question together which of the following describes the effect of a mutation in the LA O region of eli on transcription. So we want to know if we have a mutation in the lack o region of ecoli will transcription proceed normally be reduced by still inducible, be constituted will be inducible but not by lactose or answer choice. E none of the above. So first, let's recall what the lack o region is, which we know the lack o region refers to the operator region in the lack operon. And this is the region that is responsible or v finding of the lack repressor protein or R N A lime, which we know that the lac repressor protein when binded to the lac O region prevents transcription. Since the binding of that lac repressor protein means that R N A polymerase does not bind. And R N A polymerase is responsible for allowing inscription, this R N A polymerase binds to the operator region in the lac operon and starts transcription. So if we have a mutation in that operator region in the lac operon, a mutation in lack O would mean that the lack repressor protein you're not bind. And since that lack repressor protein is what prevents transcription from occurring. The lac repressor protein not being able to bind to the operator region in the lac operon would mean that the process of transcription is constant since the lac repressor protein is what stops transcription from occurring. And if there is that mutation in the lac operon, resulting in the lac repressor protein, not being able to bind R N A polymerase will stay bound to the lac O region, allowing transcription to occur in the process of transcription will be constant. So that means that transcription will be constituted, which is answer choice. C the correct answer since a mutation in the lack of region of ecoli will prevent that lac repressor protein from being able to bind. And R N A polymerase will allow the process of transcription to be constituted. So answer choice C transcription will be constituted is the only effect of that mutation. I hope you found this video to be helpful. Thank you and goodbye.

Suppose that base substitution mutations sufficient to eliminate the function of the operator regions listed below were to occur. For each case, describe how transcription or life cycle would be affected.
lacO mutation in E. coli

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Key Concepts

Operator Regions

Lac Operon

Transcription Regulation