Describe and give an example (real or hypothetical) of each of...

Question

Describe and give an example (real or hypothetical) of each of the following:

Enhanceosome action

Accepted Answer

Welcome back, everyone. Let's look at our next question. It says, which of the following statements best describes the action of an enhance ozone A. It inhibits transcription by binding to the promoter region of a gene B. It recruits R N A polymerase to the promoter region of a gene to initiate transcription. Choice. C. It enhances transcription by binding to specific transcription factors and co activators to increase the rate of transcription or choice D. It promotes the formation of chromatin loops to silence gene expression. Well, we can, even if we don't remember exactly what an enhances is, we can actually eliminate some answer choices right away. If we look at that phrase and or that portion of the word enhance, we're gonna think about enhancing or increasing. So that can lead us to feeling pretty confident that we could eliminate choice A which says it inhibits transcription because if we're talking about something that has an enhancing activity, presumably it's not going to inhibit transcription and choice D says, which says it promotes the formation of chromatin loops to silence gene expression again, pretty safe to eliminate that. Since we're gonna be talking about enhancing non silencing. So we're down to recruiting DNA polymerase to the promoter, to initiate transcription or enhancing transcription by binding to specific transcription factors to increase the rate of transcription. Well, again, even if I don't recall exactly what it is, I would go ahead and choose choice C that it enhances transcription. And in this case, that is indeed correct. That's what an enhanced zom does and enhance oom. And we can now look at the ending of this word that ozone we think of like a nucleosome is a protein complex. Usually when you see that ending, you're thinking of something with multiple parts that work together that binds to an enhancer region. So a specific transcription factor and co or co activators may be involved that bind with this protein complex and cause it to bind to the enhancer region of your gene. And the result is increased transcription, you've enhanced the rate of transcription of the gene. Now, when we look at Choice B, part of the way it enhances transcription may be helping to recruit R N A polymerase to the promoter region, maybe it helps it bind more tightly, maybe it helps make it more efficient in getting there. But since choice B says it recruits R N A plym to initiate transcription, it's not as good an answer. We're looking for the best description of the action of enhanced. So we would be looking at increasing transcription, enhancing transcription rather than initiating transcription. So again, the best description for the action of an enhanced ZOM is choice C it enhances transcription by binding to specific transcription factors and Coors to increase the rate of transcription. See you in the next video.

Describe and give an example (real or hypothetical) of each of the following:
Enhanceosome action

Key Concepts

Enhanceosome

Transcription Factors

Gene Expression Regulation

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