Nitrous acid and 5-bromodeoxyuracil (BrdU) alter DNA by different mechanisms. What type of mutation does each compound produce?

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Hey, everyone. Let's take a look at this question. Together. Aflatoxin causes the formation of adducts with DNA primarily at guanine bases forming Aflatoxin DNA adducts. These adducts can lead to mis pairing during DNA replication resulting in nucleotide substitutions or deletions. These types of mutations are considered which are they point mutations, chromosomal mutations inversions or transcations. Let's work this problem out together to try to figure out which of the following types of mutations is the correct one. So we are looking for a type of mutation in which we have mis pairing during DNA replication that results in nucleotide substitutions or deletions. We are looking for a type of mutation that occurs in DNA or R N A sequences. And since we are looking for those mutations in the DNA or R N A sequence, we are looking for nucleotide mutations. And so looking at our answer choices, we can see that answer choice B says chromosomal mutations which is incorrect since we are looking for those nucleotide mutations, and we can eliminate answer choice C and answer choice D. Since inversions and translocation are type of Chromos normal mutation leaving us with the only remaining answer which is answer choice. A point mutation, which is the correct answer since a point mutation is a nucleotide mutation in which the nucleotide is substituted or deleted. So answer choice. A point mutation is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

Nitrous acid and 5-bromodeoxyuracil (BrdU) alter DNA by different mechanisms. What type of mutation does each compound produce?

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Key Concepts

Nitrous Acid Mechanism

5-Bromodeoxyuracil (BrdU) Mechanism

Types of Mutations