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Ch. 2 - Transmission Genetics
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 2, Problem 14b

An experienced goldfish breeder receives two unusual male goldfish. One is black rather than gold, and the other has a single tail fin rather than a split tail fin. The breeder crosses the black male to a female that is gold. All the F₁ are gold. She also crosses the single-finned male to a female with a split tail fin. All the F₁ have a split tail fin. She then crosses the black male to F₁ gold females and, separately, crosses the single-finned male to F₁ split-finned females. The results of the crosses are shown below.
Results of goldfish breeding experiments showing offspring color and fin type from specific crosses.
Is black color dominant or recessive? Explain. Is single tail dominant or recessive? Explain.

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Step 1: Analyze the first cross (Black male x Gold female). All the F₁ offspring are gold. This suggests that the gold phenotype is dominant over the black phenotype. If black were dominant, we would expect at least some of the F₁ offspring to be black.
Step 2: Analyze the second cross (Single-finned male x Split-finned female). All the F₁ offspring have split fins. This suggests that the split fin phenotype is dominant over the single fin phenotype. If single fin were dominant, we would expect at least some of the F₁ offspring to have single fins.
Step 3: Examine the results of the second-generation cross (Black male x F₁ gold female). The offspring are approximately 50% gold and 50% black. This 1:1 ratio is consistent with a test cross where the F₁ gold female is heterozygous (Gg) and the black male is homozygous recessive (gg). This further supports that black is recessive.
Step 4: Examine the results of the second-generation cross (Single-finned male x F₁ split-finned female). The offspring are approximately 50% split fin and 50% single fin. This 1:1 ratio is consistent with a test cross where the F₁ split-finned female is heterozygous (Ss) and the single-finned male is homozygous recessive (ss). This further supports that single fin is recessive.
Step 5: Conclude that the black phenotype is recessive to gold, and the single fin phenotype is recessive to split fin. The observed ratios in the second-generation crosses align with Mendelian inheritance patterns for a single gene with two alleles, one dominant and one recessive.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Dominance in Genetics

Dominance refers to the relationship between alleles, where one allele can mask the expression of another. In a dominant-recessive relationship, the dominant allele will determine the phenotype when present, while the recessive allele will only be expressed in a homozygous state. Understanding this concept is crucial for interpreting the results of genetic crosses, as it helps predict the phenotypic ratios of offspring based on parental genotypes.
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Variations on Dominance

Phenotypic Ratios

Phenotypic ratios are the relative frequencies of different phenotypes in the offspring resulting from a genetic cross. By analyzing the offspring's traits, such as color and fin type in this case, one can infer the underlying genotypes of the parents. The observed ratios can indicate whether a trait is dominant or recessive, providing insights into the inheritance patterns of specific characteristics.
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Monohybrid Cross

A monohybrid cross involves breeding individuals that differ in a single trait, allowing the study of inheritance patterns for that trait. In this scenario, the crosses between the black and gold goldfish, as well as the single-finned and split-finned goldfish, exemplify monohybrid crosses. Analyzing the offspring from these crosses helps determine the dominance of traits, as the resulting phenotypic ratios can reveal whether the traits are inherited in a dominant or recessive manner.
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Related Practice
Textbook Question

A male mouse with brown fur color is mated to two different female mice with black fur. Black female 1 produces a litter of 9 black and 7 brown pups. Black female 2 produces 14 black pups.

Choose symbols for each allele, and identify the genotypes of the brown male and the two black females.

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Textbook Question

The following figure shows the results of Mendel's test-cross analysis of independent assortment. In this experiment, he first crossed pure-breeding round, yellow plants to pure-breeding wrinkled, green plants. The round yellow are crossed to pure-breeding wrinkled, green plants. Use chi-square analysis to show that Mendel's results do not differ significantly from those expected.

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Textbook Question

An experienced goldfish breeder receives two unusual male goldfish. One is black rather than gold, and the other has a single tail fin rather than a split tail fin. The breeder crosses the black male with a female that is gold. All the F₁ are gold. She also crosses the single-finned male to a female with a split tail fin. All the F₁ have a split tail fin. She then crosses the black male to F₁ gold females and, separately, crosses the single-finned male to F₁ split-finned females. The results of the crosses are shown below.


  Black male x F₁ gold female:

    Gold        32

    Black       34

  Single-finned male x F₁ split-finned female:

    Split fin       41

    Single fin    39

What do the results of these crosses suggest about the inheritance of color and tail fin shape in goldfish?

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Textbook Question

An experienced goldfish breeder receives two unusual male goldfish. One is black rather than gold, and the other has a single tail fin rather than a split tail fin. The breeder crosses the black male to a female that is gold. All the F₁ are gold. She also crosses the single-finned male to a female with a split tail fin. All the F₁ have a split tail fin. She then crosses the black male to F₁ gold females and, separately, crosses the single-finned male to F₁ split-finned females. The results of the crosses are shown below.

  Black male x F₁ gold female:

    Gold         32

    Black        34

  Single-finned male x F₁ split-finned female:

    Split fin        41

    Single fin     39

Use chi-square analysis to test your hereditary hypothesis for each trait.

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Textbook Question

The accompanying pedigree shows the transmission of albinism (absence of skin pigment) in a human family.

What is the most likely mode of transmission of albinism in this family? 

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Textbook Question

The accompanying pedigree shows the transmission of albinism (absence of skin pigment) in a human family.

Using allelic symbols of your choice, identify the genotypes of the male and his two mates in generation I. 

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