Textbook Question
The frequency of an autosomal recessive condition is 0.001 (1 in 1000) in a population.
Assuming individuals mate at random, what is the chance that two heterozygous individuals will mate?
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Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
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Sanders 3rd EditionCh. 20 - Population Genetics and Evolution at the Population, Species, and Molecular LevelsProblem 34a
Sanders 3rd EditionCh. 20 - Population Genetics and Evolution at the Population, Species, and Molecular LevelsProblem 34aChapter 20, Problem 34a
Evaluate the following pedigree, and answer the questions below. Which individual(s) in this family is/are inbred?
Verified step by step guidance1
Step 1: Understand the concept of inbreeding. Inbreeding occurs when individuals who are closely related genetically (e.g., cousins, siblings) reproduce. This increases the likelihood of homozygosity for recessive alleles, which can lead to genetic disorders.
Step 2: Analyze the pedigree chart provided. Look for instances where individuals share common ancestors, indicating a potential inbreeding event. Specifically, trace the lineage of each individual to identify shared ancestry.
Step 3: Focus on the offspring of unions between individuals who are related. In the chart, identify any individuals whose parents are cousins or otherwise closely related.
Step 4: Highlight the individuals who are products of such unions. For example, if two cousins have children, those children are considered inbred because their parents share a common ancestor.
Step 5: Confirm the inbred individuals by verifying the shared ancestry of their parents. Use the pedigree chart to ensure that the parents are indeed related and that the offspring are direct descendants of this union.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Pedigree Analysis
Pedigree analysis is a method used to study the inheritance patterns of traits in families. It involves creating a diagram that represents family relationships and the transmission of genetic traits across generations. By analyzing the pedigree, one can identify carriers of specific traits, determine the mode of inheritance, and assess the likelihood of traits appearing in future generations.
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Pedigree Flowchart
Inbreeding
Inbreeding refers to the mating of individuals who are closely related genetically, which can increase the probability of offspring inheriting genetic disorders. In a pedigree, inbreeding is often indicated by a mating between individuals who share a common ancestor. This practice can lead to a higher incidence of homozygous recessive conditions due to the increased likelihood of both parents carrying the same recessive alleles.
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Symbols in Pedigrees
In pedigree charts, specific symbols are used to represent individuals and their relationships. Males are typically represented by squares, while females are represented by circles. A filled symbol indicates an affected individual, while an empty symbol indicates an unaffected individual. Understanding these symbols is crucial for interpreting the pedigree and identifying patterns of inheritance, including potential inbreeding.
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Related Practice
Textbook Question
Evaluate the following pedigree, and answer the questions below for individual IV-1. Is IV-1 an inbred individual? If so, who is/are the common ancestor(s)?
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Textbook Question
Evaluate the following pedigree, and answer the questions below for individual IV-1. What is F for this individual?
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Textbook Question
Evaluate the following pedigree, and answer the questions below. Who is/are the common ancestor(s) of the inbred individual(s)?
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Textbook Question
Evaluate the following pedigree, and answer the questions below. Calculate F for any inbred members of this family.
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Textbook Question
The following is a partial pedigree of the British royal family. The family contains several inbred individuals and a number of inbreeding pathways. Carefully evaluate the pedigree, and identify the pathways and common ancestors that produce inbred individuals A (Alice in generation IV), B (George VI in generation VI), and C (Charles in generation VIII).
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