Telomeres are found at the ends of eukaryotic chromosomes. What is the functional role of telomeres?

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Everyone. Let's take a look at this question together. Which of the following is a consequence of shortening of telomeres. Is it answer choice? A cellular sentence? Answer choice B chromosome instability, answer choice C cancer or answer choice D. All of the above. Let's work this problem out together to try to figure out which of the following answer choices is a consequence of the shortening of telomeres. So to solve this question, let's break down each answer choice to try to figure out if it is a consequence of the shortening of telomeres. Answer choice A says cellular sentence which we note that the state of sentience refers to when cells stop dividing and they become metabolically unstable. And we want to know if cellular sentence is a consequence of the shortening of telomeres, which we know that when those telomeres become too short, the cells can enter that state of sentence in which they stop dividing and become metabolically unstable. So in answer choice A is a consequence of the shortening of telomeres. But let's double check with the rest of the answer choices before making our selection. Answer choice B says chromosome instability, which we know that those telomeres protect chromosome ends from degradation and fusion. And when those telomeres become too short, they can no longer adequately protect the ends of the chromosomes. And that causes those chromosomes to become unstable. So, chromosome instability is also a consequence of the shortening of telomeres. And lastly answer choice C cancer, which we know that those unprotected chromosome ends can trigger a DNA damage response. And those unprotected chromosome ends are a result of chromosome instability, which is a result of the shortening of telomeres. So answer choice C is also a consequence of the shortening of telomeres, which means that answer choices A B and C are all consequences. So answer choice D, all of the above is the correct answer because we know that when those telomeres become too short, the cells can enter a state of sentience as well as the chromosomes becoming unstable since the telomeres are too short and can no longer adequately protect the chromosome ends. And those unprotected chromosome ends can trigger a DNA damage response such as cancer. So answer choices A B and C are all correct answers and answer choice. D, all of the above is the most appropriate answer. Choice, making it the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

Telomeres are found at the ends of eukaryotic chromosomes. What is the functional role of telomeres?

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Key Concepts

Telomeres

Chromosome Stability

Cellular Aging