Textbook Question
The three major forms of RNA (mRNA, tRNA, and rRNA) interact during translation.
Which form of RNA is least stable in eukaryotes? Why is this form least stable?
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Ch. 9 - The Molecular Biology of Translation
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
Chapter 9, Problem 17
The line below represents a mature eukaryotic mRNA. The accompanying list contains many sequences or structures that are part of eukaryotic mRNA. A few of the items in the list, however, are not found in eukaryotic mRNA. As accurately as you can, show the location, on the line, of the sequences or structures that belong in eukaryotic mRNA; then, separately, list the items that are not part of eukaryotic mRNA.
5′ ____________________________ 3′
a. stop codon
b. poly-A tail
c. intron
d. 3' UTR
e. promoter
f. start codon
g. AAUAAA
h. 5' UTR
i. 5' cap
j. termination sequence
Verified step by step guidance1
Identify the components that are part of a mature eukaryotic mRNA.
Recognize that a mature eukaryotic mRNA includes a 5' cap, 5' UTR, start codon, coding sequence, stop codon, 3' UTR, and a poly-A tail.
Place the 5' cap at the beginning of the mRNA sequence, followed by the 5' UTR.
Locate the start codon after the 5' UTR, followed by the coding sequence, and then the stop codon.
Position the 3' UTR after the stop codon, followed by the poly-A tail at the end of the mRNA sequence.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Eukaryotic mRNA Structure
Eukaryotic mRNA is a complex molecule that undergoes several modifications after transcription. It typically includes a 5' cap, a 5' untranslated region (UTR), coding sequences (exons), a 3' UTR, and a poly-A tail. These components play crucial roles in mRNA stability, translation initiation, and regulation of gene expression.
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Chromosome Structure
Introns and Exons
In eukaryotic genes, exons are the coding sequences that are retained in the mature mRNA, while introns are non-coding sequences that are removed during RNA splicing. This process allows for the generation of diverse protein isoforms through alternative splicing, which can significantly impact gene function and regulation.
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Transcription and Translation
Transcription is the process by which DNA is copied into mRNA, while translation is the subsequent process where ribosomes synthesize proteins based on the mRNA sequence. Understanding these processes is essential for identifying which elements are present in mature mRNA and their roles in protein synthesis.
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Related Practice
Textbook Question
The three major forms of RNA (mRNA, tRNA, and rRNA) interact during translation.
Compared to the average stability of mRNA in E. coli, is mRNA in a typical human cell more stable or less stable? Why?
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Textbook Question
The accompanying figure contains sufficient information to fill in every row. Use the information provided to complete the figure.
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Textbook Question
After completing Problem 17, carefully draw a line below the mRNA to represent its polypeptide product in accurate alignment with the mRNA. Label the N-terminal and C-terminal ends of the polypeptide. Carefully draw two lines above and parallel to the mRNA, and label them 'coding strand' and 'template strand.' Locate the DNA promoter sequence. Identify the locations of the nucleotide and of a transcription termination sequence.
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Textbook Question
Define and describe the differences in the primary, secondary, and tertiary structures of a protein.
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Textbook Question
Describe the roles and relationships between tRNA synthetases and tRNA molecules.
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