What level of protein structure is involved in the formation of an enzyme’s active site?

Question

Accepted Answer

Hello everyone. Our next question says the formation of an enzymes active site involves different levels of protein structure, which level of protein structure is or are involved in the formation of an enzymes active site. A the primary structure of a protein directly forms the enzymes act toy B the secondary structure including alpha helices and beta sheets plays a direct role in forming the enzyme's active site. See, the tertiary structure is crucial for forming the enzyme's active site by providing the 3d folding necessary for its formation or d the quaternary structure is essential for forming the enzymes active sites in all types of enzymes. So choice D we can rule out right away because recall that Quain structure has to do with how multiple peptide changes are arranged. So it's not essential in all types of enzymes but only in multi subunit enzymes. So it doesn't even apply to enzymes that have only one peptide chain. So let's think through our other answer. Choices. Choice A is going to be incorrect the way it phrases it, it says that it directly forms the enzyme's active site. The primary structures of course is the sequence of amino acids. So while the particular amino acids that are within the active site are important in terms of how are they interacting with a substrate? Recall that the 3d shape of the enzymes active site is important in the way it fits the substrate. So since we're talking about 3d shape, that's going to focus us on choice C that the tertiary structure is crucial for form the enzymes active site by providing a 3d folding necessary for its formation. Whenever we think of protein folding, we should think of that tertiary structure. So then choice B is also incorrect secondary structure with alpha helices and beta sheets does not play a direct role in forming that active site which has this resemblance of specific shape to. Again, we recall that the active site of an enzyme has to fit that substrate. The structures need to really resemble each other. And then when bonding occurs between the substrate and the active site, there's a confirmational change in this model in the enzyme. So again, we're talking about the active site for an enzyme and a question about which level of protein structure is involved in the formation of enzymes, active sites. And choice C the tertiary structure is crucial, performing the enzymes active site by producing the 3d folding necessary for its formation. See you in the next video.

What level of protein structure is involved in the formation of an enzyme’s active site?

Verified video answer for a similar problem:

Key Concepts

Protein Structure Levels

Active Site

Enzyme Functionality