Explain how blood, being a liquid, enables all its components (formed elements and plasma) to perform their functions.
Predict how abnormal hemoglobin proteins that contain only two iron ions, instead of four, would affect homeostasis.
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Key Concepts
Hemoglobin Structure and Function
Homeostasis
Compensatory Mechanisms
The anticoagulant drug warfarin primarily disrupts the extrinsic/tissue factor coagulation pathway. Explain why disrupting only this pathway disrupts the entire coagulation cascade.
Elise is a 36-year-old woman who has volunteered to donate red bone marrow to a patient in need of a bone marrow transplant for aplastic anemia. The physician performing the bone marrow extraction is an intern, and it is her first time doing the procedure. She asks that you prepare a site on Elise's tibia for the procedure. Is this a good place for red bone marrow to be extracted, considering Elise's age? Why or why not? Can you suggest an alternative location? Explain.
Cirrhosis of the liver often reduces production of many types of plasma proteins, including albumin and clotting factors. Predict the effects on the body of decreased numbers of these proteins in the plasma. Would this also affect the number of γ-globulins in the plasma? Why or why not?
Which of the following plasma proteins is responsible for osmotic pressure?
a. γ-Globulins
b. Albumin
c. α-Globulins
d. Clotting proteins
Predict the effects of each of the following on systemic arterial blood pressure:
The practice of 'blood doping,' which increases the number of red blood cells in the blood
