Predict the F₁ and F₂ results of crossing a male fowl that is cock-feathered with a true-breeding hen-feathered female fowl. Recall that these traits are sex limited.

Contrast penetrance and expressivity as the terms relate to phenotypic expression.
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Key Concepts
Penetrance
Expressivity
Genotype-Phenotype Relationship
Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?
Discuss the topic of phenotypic expression and the many factors that impinge on it.
Labrador retrievers may be black, brown (chocolate), or golden (yellow) in color (see chapter-opening photo). While each color may breed true, many different outcomes are seen when numerous litters are examined from a variety of matings where the parents are not necessarily true breeding. Following are just some of the many possibilities.
(a) black x brown → all black
(b) black x brown → 1/2 black, 1/2 brown
(c) black x brown → 3/4 black, 1/4 golden
(d) black x golden → all black
(e) black x golden → 4/8 golden 3/8 black 1/8 brown
(f) black x golden → 2/4 golden 1/4 black 1/4 brown
(g) brown x brown → 3/4 brown 1/4 golden
(h) black x black → 9/16 black 4/16 golden, 3/16 brown
Propose a mode of inheritance that is consistent with these data, and indicate the corresponding genotypes of the parents in each mating. Indicate as well the genotypes of dogs that breed true for each color.
A true-breeding purple-leafed plant isolated from one side of El Yunque, the rain forest in Puerto Rico, was crossed to a true-breeding white variety found on the other side. The F₁ offspring were all purple. A large number of F₁ x F₁ crosses produced the following results:
purple: 4219, white: 5781 (Total = 10,000)
Propose an explanation for the inheritance of leaf color. As a geneticist, how might you go about testing your hypothesis? Describe the genetic experiments that you would conduct.
In Dexter and Kerry cattle, animals may be polled (hornless) or horned. The Dexter animals have short legs, whereas the Kerry animals have long legs. When many offspring were obtained from matings between polled Kerrys and horned Dexters, half were found to be polled Dexters and half polled Kerrys. When these two types of F₁ cattle were mated to one another, the following F₂ data were obtained:
3/8 polled Dexters
3/8 polled Kerrys
1/8 horned Dexters
1/8 horned Kerrys
A geneticist was puzzled by these data and interviewed farmers who had bred these cattle for decades. She learned that Kerrys were true breeding. Dexters, on the other hand, were not true breeding and never produced as many offspring as Kerrys. Provide a genetic explanation for these observations.
