Three-spined stickleback fish live in lakes formed when the last ice age ended 10,000 to 15,000 years ago. In lakes where the sticklebacks are prey for larger fish, they develop 35 bony plates along their body as armor. In contrast, sticklebacks in lakes where there are no predators develop only a few or no bony plates. In crosses between fish of the two different morphologies, the lack of bony armor segregates as a recessive trait that maps to the ectodermal dysplasin (Eda) gene. Comparisons between the Eda-coding regions of the armored and nonarmored fish revealed no differences. How can you explain this result?

Homeotic genes are thought to regulate each other. What aspect of the phenotype of apetala2 agamous double mutants indicates that these two genes act antagonistically?
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Key Concepts
Homeotic Genes
Antagonistic Gene Interaction
Phenotypic Analysis
Three-spined stickleback fish live in lakes formed when the last ice age ended 10,000 to 15,000 years ago. In lakes where the sticklebacks are prey for larger fish, they develop 35 bony plates along their body as armor. In contrast, sticklebacks in lakes where there are no predators develop only a few or no bony plates. Loss-of-function mutations in the coding region of the homologous gene in humans result in loss of hair, teeth, and sweat glands, as in the toothless men of Sind (India). What does this suggest about hair, teeth, and sweat glands in humans?
The flowering jungle plant Lacandonia schismatica, discovered in southern Mexico, has a unique floral structure. Petal-like organs are in the outer whorls surrounding a number of carpels, and stamens are in the center of the flower. Closely related species are dioecious; female plants bear flowers that resemble those of Lacandonia, but without the central stamens. What type of mutation could have resulted in the evolution of Lacandonia flowers?
Homeotic genes are thought to regulate each other. Are similar interactions observed between Hox genes?
Dipterans (two-winged insects) are thought to have evolved from a four-winged ancestor that had wings on both T2 and T3 thoracic segments, as in extant butterflies and dragonflies. Describe an evolutionary scenario for the evolution of dipterans from four-winged ancestors. What types of mutations could lead to a butterfly developing with only two wings?
Basidiomycota is a monophyletic group of fungi that includes most of the common mushrooms. You are interested in the development of the body plan of mushrooms. How would you identify the genes required for patterning during mushroom development?
