What is a quantitative trait locus (QTL)? Suppose you wanted to search for QTLs influencing fruit size in tomatoes. Describe the general structure of a QTL experiment, including the kind of tomato strains you would use, how molecular markers should be distributed in the genome, how the genetic marker alleles should differ between the two strains, and how you would use the F₁ progeny in a subsequent cross to obtain information about the possible location(s) of QTLs of interest.

In a line of cherry tomatoes, the average fruit weight is 16 g. A plant producing tomatoes with an average weight of 12 g is used in one self-fertilization cross to produce a line of smaller tomatoes, and a plant producing tomatoes of 24 g is used in a second cross to produce larger tomatoes. What is the selection differential (S) for fruit weight in each cross?
Verified step by step guidance
Verified video answer for a similar problem:
Key Concepts
Selection Differential (S)
Phenotypic Variation
Self-Fertilization in Plants
In Nicotiana, two inbred strains produce long (PL) and short (PS) corollas. These lines are crossed to produce F₁, and the F₁ are crossed to produce F₂ plants in which corolla length and variance are measured. The following table summarizes the mean and variance of corolla length in each generation. Calculate H² for corolla length in Nicotiana.
Suppose the length of maize ears has narrow sense heritability (h²) of 0.70. A population produces ears that have an average length of 28 cm, and from this population a breeder selects a plant producing 34-cm ears to cross by self-fertilization. Predict the selection differential (S) and the response to selection (R) for this cross.
In a line of cherry tomatoes, the average fruit weight is 16 g. A plant producing tomatoes with an average weight of 12 g is used in one self-fertilization cross to produce a line of smaller tomatoes, and a plant producing tomatoes of 24 g is used in a second cross to produce larger tomatoes. If narrow sense heritability (h²) for this trait is 0.80, what are the expected responses to selection (R) for fruit weight in the crosses?
Two pure-breeding wheat strains, one producing dark red kernels and the other producing white kernels, are crossed to produce F₁ with pink kernel color. When an F₁ plant is self-fertilized and its seed collected and planted, the resulting F₂ consists of 160 plants with kernel colors as shown in the following table.
Based on the F₂ progeny, how many genes are involved in kernel color determination?
Two pure-breeding wheat strains, one producing dark red kernels and the other producing white kernels, are crossed to produce F₁ with pink kernel color. When an F₁ plant is self-fertilized and its seed collected and planted, the resulting F₂ consists of 160 plants with kernel colors as shown in the following table.
How many additive alleles are required to explain the five phenotypes seen in the F₂?
