Textbook Question
Draw a separate hypothetical pedigree identifying the inbred individuals and the inbreeding pathways for each of the following inbreeding coefficients:
F=4(1/2)⁶
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Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
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Sanders 3rd EditionCh. 20 - Population Genetics and Evolution at the Population, Species, and Molecular LevelsProblem 36d
Sanders 3rd EditionCh. 20 - Population Genetics and Evolution at the Population, Species, and Molecular LevelsProblem 36dChapter 20, Problem 36d
Draw a separate hypothetical pedigree identifying the inbred individuals and the inbreeding pathways for each of the following inbreeding coefficients:
F=2(1/2)⁷
Verified step by step guidance1
Step 1: Understand the concept of inbreeding coefficient (F). The inbreeding coefficient quantifies the probability that two alleles at a locus are identical by descent. It is calculated based on the pathways of inheritance and the degree of relatedness between parents.
Step 2: Recognize that the formula for the inbreeding coefficient is F = Σ(1/2)^n, where n represents the number of individuals in the inbreeding pathway connecting the parents of the individual being analyzed. In this case, F = 2(1/2)^7.
Step 3: Draw a hypothetical pedigree. Start by identifying the individual whose inbreeding coefficient is being calculated. This individual will be the focal point of the pedigree. Label this individual clearly.
Step 4: Trace the inbreeding pathways. Since the formula includes (1/2)^7, this indicates that there are 7 generations in the pathway connecting the parents of the focal individual. Draw the pedigree to reflect this, showing the common ancestor(s) and the repeated mating events that lead to the focal individual.
Step 5: Highlight the inbred individuals and the pathways. Mark the individuals in the pedigree who are inbred (those with an inbreeding coefficient greater than 0). Clearly indicate the pathways that contribute to the calculation of F = 2(1/2)^7, ensuring the pedigree visually represents the generational connections and shared ancestry.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Inbreeding Coefficient (F)
The inbreeding coefficient (F) quantifies the probability that two alleles at a locus are identical by descent. It ranges from 0 (no inbreeding) to 1 (complete inbreeding). In this context, F=2(1/2)⁷ indicates a specific level of inbreeding, which can be calculated to understand the genetic relatedness of individuals in a pedigree.
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08:52
F Factor and Hfr
Pedigree Analysis
Pedigree analysis is a method used to trace the inheritance of traits and genetic disorders through generations. It involves creating a diagram that represents family relationships and genetic connections. By analyzing a pedigree, one can identify inbred individuals and their pathways, which is essential for understanding the implications of inbreeding on genetic diversity and health.
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01:59Pedigree Flowchart
Inbreeding Pathways
Inbreeding pathways refer to the specific routes through which genetic material is passed between related individuals in a pedigree. These pathways illustrate how alleles can be inherited from common ancestors, leading to increased homozygosity. Understanding these pathways is crucial for identifying inbred individuals and assessing the potential risks associated with inbreeding, such as the expression of deleterious traits.
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Related Practice
Textbook Question
Draw a separate hypothetical pedigree identifying the inbred individuals and the inbreeding pathways for each of the following inbreeding coefficients:
F=2(1/2)⁵
694
views
Textbook Question
Draw a separate hypothetical pedigree identifying the inbred individuals and the inbreeding pathways for each of the following inbreeding coefficients:
F=4(1/2)⁸
427
views
Textbook Question
The human melanocortin 1 receptor gene (MC1R) plays a major role in producing eumelanin, a black-brown pigment that helps determine hair color and skin color. Jonathan Rees and several colleagues (J. L. Rees et al., Am. J. Human Genet. 66(2000): 1351–1361) studied multiple MC1R alleles in African and European populations. Although this research found several MC1R alleles in African populations, MC1R alleles that decrease the production of eumelanin were rare. In contrast, several alleles decreasing eumelanin production were found in European populations. How can these results be explained by natural selection?
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Textbook Question
Achromatopsia is a rare autosomal recessive form of complete color blindness that affects about 1 in 20,000 people in most populations. People with this disorder see only in black and white and have extreme sensitivity to light and poor visual acuity. On Pingelap Island, one of a cluster of coral atoll islands in the Federated States of Micronesia, approximately 10% of the 3000 indigenous Pingelapese inhabitants have achromatopsia.Achromatopsia was first recorded on Pingelap in the mid-1800s, about four generations after a typhoon devastated Pingelap and reduced the island population to about 20 people. All Pingelapese with achromatopsia trace their ancestry to one male who was one of the 20 typhoon survivors. Provide a genetic explanation for the origin of achromatopsia on Pingelap, and explain the most likely evolutionary model for the high frequency there of achromatopsia.
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Textbook Question
New allopolyploid plant species can arise by hybridization between two species. If hybridization occurs between a diploid plant species with 2n = 14 and a second diploid species with 2n = 22, the new allopolyploid would have 36 chromosomes. Is it likely that sexual reproduction between the allopolyploid species and either of its diploid ancestors would yield fertile progeny? Why or why not?
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