Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Rearrangements: Inversions
Problem 10
Textbook Question
Inversions are said to 'suppress crossing over.' Is this terminology technically correct? If not, restate the description accurately.
Verified step by step guidance1
Understand the concept of chromosomal inversions: an inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end.
Recall that crossing over refers to the exchange of genetic material between homologous chromosomes during meiosis, which increases genetic diversity.
Recognize that inversions do not prevent the physical process of crossing over from occurring; rather, they affect the outcome of crossing over within the inverted segment.
Learn that crossing over within an inversion loop can produce abnormal chromatids (e.g., duplications or deletions), which are often inviable or selected against, leading to a reduction in viable recombinant offspring.
Therefore, the term 'suppress crossing over' is technically inaccurate; a more precise description is that inversions 'reduce the recovery of recombinant chromatids' or 'reduce the viability of crossover products' within the inverted region.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Chromosomal Inversions
Chromosomal inversions occur when a segment of a chromosome breaks off, flips, and reinserts in the reverse orientation. This rearrangement can affect gene order and pairing during meiosis, potentially leading to altered genetic outcomes.
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Crossing Over During Meiosis
Crossing over is the exchange of genetic material between homologous chromosomes during prophase I of meiosis. It increases genetic diversity by producing new allele combinations but requires proper alignment of homologous regions.
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Crossing Over Terminology
Effect of Inversions on Recombination
Inversions do not completely prevent crossing over but suppress viable recombinant products because crossover within the inverted region can produce unbalanced or inviable gametes. Thus, the term 'suppress crossing over' is better described as 'suppress recovery of recombinant chromatids.'
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Textbook Question
What roles have inversions and translocations played in the evolutionary process?
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