Which observation suggested to Sutherland the involvement of a se...

Question

Which observation suggested to Sutherland the involvement of a second messenger in epinephrine’s effect on liver cells?
a. Enzymatic activity was proportional to the amount of calcium added to a cell-free extract.
b. Receptor studies indicated that epinephrine was a ligand.
c. Glycogen breakdown was observed only when epinephrine was administered to intact cells.
d. Glycogen breakdown was observed only when epinephrine and glycogen phosphorylase were mixed.

Accepted Answer

Hi everyone here, we have a question asking what is the role of a secondary messenger and cell signaling? A relay? The signal received at the cell surface receptor? This is correct. 2nd messengers are molecules that carry the signals from that are received at the cell surface receptor to intracellular target molecules, and those target molecules can be in the cytoplasm or the nucleus be bind to the login. This is incorrect. See carry the login to the nucleus of the cell. This is incorrect, so D. Is also incorrect. So our correct answer here is a relay, the signal received at the cell surface receptor. And again, that signal will go either to the cytoplasm or the nucleus. Thank you for watching. Bye.

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