How do we know that DNA also serves as the genetic material in eukaryotes such as humans?

Most center around DNA and RNA and their role of serving as the genetic material. Write a short essay that contrasts these molecules, including a comparison of advantages conferred by their structure that each of them has over the other in serving in this role.
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Key Concepts
Structural Differences Between DNA and RNA
Stability and Function in Genetic Information Storage
Functional Roles and Advantages in Genetic Processes
How was it determined that the structure of DNA is a double helix with the two strands held together by hydrogen bonds formed between complementary nitrogenous bases?
How do we know that G pairs with C and that A pairs with T as complementary base pairs are formed?
Discuss the reasons proteins were generally favored over DNA as the genetic material before 1940. What was the role of the tetranucleotide hypothesis in this controversy?
Contrast the contributions made to an understanding of transformation by Griffith and by Avery and his colleagues.
When Avery and his colleagues had obtained what was concluded to be the transforming factor from the IIIS virulent cells, they treated the fraction with proteases, RNase, and DNase, followed in each case by the assay for retention or loss of transforming ability. What were the purpose and results of these experiments? What conclusions were drawn?
