M. Klemke et al. (2001) discovered an interesting coding phenomenon in which an exon within a neurologic hormone receptor gene in mammals appears to produce two different protein entities (and ALEX). The following is the DNA sequence of the exon's end derived from a rat.
5'-gtcccaaccatgcccaccgatcttccgcctgcttctgaagATGCGGGCCCAG
The lowercase letters represent the initial coding portion for the protein, and the uppercase letters indicate the portion where the ALEX entity is initiated. (For simplicity, and to correspond with the RNA coding dictionary, it is customary to represent the coding (non-template) strand of the DNA segment.)
Locate the initiator codon within the ALEX segment. Are the two initiator codons in frame?

Question

M. Klemke et al. (2001) discovered an interesting coding phenomenon in which an exon within a neurologic hormone receptor gene in mammals appears to produce two different protein entities (and ALEX). The following is the DNA sequence of the exon's end derived from a rat.

5'-gtcccaaccatgcccaccgatcttccgcctgcttctgaagATGCGGGCCCAG

The lowercase letters represent the initial coding portion for the protein, and the uppercase letters indicate the portion where the ALEX entity is initiated. (For simplicity, and to correspond with the RNA coding dictionary, it is customary to represent the coding (non-template) strand of the DNA segment.)

Locate the initiator codon within the ALEX segment. Are the two initiator codons in frame?

Accepted Answer

Hello everyone welcome back. Here's our next question which of the following statements about the translation process is false. So let's look through our answer choices. Keeping in mind as we look them over the choice D. Is all options are true. So we have the possibility that we won't have a false statement and everything will be correct. So we're thinking about translation. So let's start with choice A choice A says the translation of the M. RNA sequence starts from five prime end to the three prime it and that is correct. So we'll say that can't be our answer choice. So we'll cross that off. Translation always proceeds from the five prime end of the M. R. N. A. To the 353 prime end. Choice B says the T. RNA carries the protein specified by the code in. Well this is not correct. Uh The T. R. N. A. S. Do not carry the protein. They carry the amino acid. Those monomers that make up the protein. So each T RNA binds to a code on its anti code on specifies a specific amino acid and it brings that in to add the amino acid onto the growing poly peptide. So that is a false statement and therefore Choice B must be our answer. Therefore we also know that choice D. All options are correct cannot be our answer to be thorough. We'll look at choice C choi C says the T. RNA binds the M. R. N. A. Inside the ribosome. Well this is correct. The ribosome assembles around the M. RNA to be translated and then moves along the M. R. N. A. As T N T RNA comes in and binds to its target code ons when it reaches a stop code on, the ribosome releases the newly synthesized poly peptide. Since this is correct, that is not our answer. So again, our question said. Which of the following statements about the translation process is false and the answer is Choice B. The T RNA carries the protein specified by the code on. See you in the next video.

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Key Concepts

Exons and Introns

Initiator Codon

Reading Frame