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Ch. 23 - Developmental Genetics
Klug - Concepts of Genetics  12th Edition
Klug12th EditionConcepts of Genetics ISBN: 9780135564776Not the one you use?Change textbook
Chapter 23, Problem 8

List the main classes of zygotic genes. What is the function of each class of these genes?

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Understand that zygotic genes are genes expressed in the zygote after fertilization, and they play a critical role in early embryonic development.
Identify the three main classes of zygotic genes: gap genes, pair-rule genes, and segment polarity genes.
Explain the function of gap genes: These genes define broad regions of the embryo and help establish the overall body plan by dividing the embryo into large segments.
Describe the function of pair-rule genes: These genes refine the segmentation pattern by dividing the embryo into alternating bands or stripes, which correspond to the future segments of the organism.
Clarify the function of segment polarity genes: These genes define the anterior-posterior polarity within each segment, ensuring that each segment has a distinct orientation and identity.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Zygotic Genes

Zygotic genes are genes that are expressed after fertilization, playing a crucial role in the early development of the embryo. They are typically activated in the zygote and are responsible for the initial stages of development, including cell division and differentiation. Understanding zygotic genes is essential for grasping how genetic information is utilized during the early phases of organismal development.
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Segmentation Genes

Classes of Zygotic Genes

The main classes of zygotic genes include maternal effect genes, segmentation genes, and homeotic genes. Maternal effect genes are inherited from the mother and influence early embryonic development. Segmentation genes are involved in defining the body plan by establishing segments, while homeotic genes determine the identity of these segments, ensuring that body parts develop in the correct locations.
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Gene Function in Development

Each class of zygotic genes has specific functions that contribute to the overall developmental process. Maternal effect genes set up the initial conditions for development, segmentation genes organize the body structure, and homeotic genes provide instructions for the formation of specific body parts. Understanding these functions is vital for comprehending how genetic regulation shapes the organism's form and function during development.
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