What are zygotic genes, and when are their gene products made?
Ch. 23 - Developmental Genetics

Chapter 23, Problem 8
List the main classes of zygotic genes. What is the function of each class of these genes?
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Understand that zygotic genes are genes expressed in the zygote after fertilization, and they play a critical role in early embryonic development.
Identify the three main classes of zygotic genes: gap genes, pair-rule genes, and segment polarity genes.
Explain the function of gap genes: These genes define broad regions of the embryo and help establish the overall body plan by dividing the embryo into large segments.
Describe the function of pair-rule genes: These genes refine the segmentation pattern by dividing the embryo into alternating bands or stripes, which correspond to the future segments of the organism.
Clarify the function of segment polarity genes: These genes define the anterior-posterior polarity within each segment, ensuring that each segment has a distinct orientation and identity.

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Key Concepts
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Zygotic Genes
Zygotic genes are genes that are expressed after fertilization, playing a crucial role in the early development of the embryo. They are typically activated in the zygote and are responsible for the initial stages of development, including cell division and differentiation. Understanding zygotic genes is essential for grasping how genetic information is utilized during the early phases of organismal development.
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Segmentation Genes
Classes of Zygotic Genes
The main classes of zygotic genes include maternal effect genes, segmentation genes, and homeotic genes. Maternal effect genes are inherited from the mother and influence early embryonic development. Segmentation genes are involved in defining the body plan by establishing segments, while homeotic genes determine the identity of these segments, ensuring that body parts develop in the correct locations.
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Segmentation Genes
Gene Function in Development
Each class of zygotic genes has specific functions that contribute to the overall developmental process. Maternal effect genes set up the initial conditions for development, segmentation genes organize the body structure, and homeotic genes provide instructions for the formation of specific body parts. Understanding these functions is vital for comprehending how genetic regulation shapes the organism's form and function during development.
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Functional Genomics
Related Practice
Textbook Question
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Textbook Question
What is the phenotype associated with zygotic gene mutations?
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Textbook Question
Does the maternal genotype contain zygotic genes?
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Textbook Question
Experiments have shown that any nuclei placed in the polar cytoplasm at the posterior pole of the Drosophila egg will differentiate into germ cells. If polar cytoplasm is transplanted into the anterior end of the egg just after fertilization, what will happen to nuclei that migrate into this cytoplasm at the anterior pole?
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Textbook Question
How can you determine whether a particular gene is being transcribed in different cell types?
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Textbook Question
You observe that a particular gene is being transcribed during development. How can you tell whether the expression of this gene is under transcriptional or translational control?
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