How do we know that threshold traits are actually polygenic even though they may have as few as two discrete phenotypic classes?
Ch. 25 - Quantitative Genetics and Multifactorial Traits

Chapter 25, Problem 1d
How do we assess environmental factors to determine if they impact the phenotype of a quantitatively inherited trait?
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Identify the quantitative trait of interest and measure its phenotype across a population exposed to different environmental conditions.
Collect data on environmental variables that could influence the trait, such as temperature, nutrition, or stress levels, ensuring these factors vary systematically or naturally among the individuals.
Use statistical methods like analysis of variance (ANOVA) or regression analysis to compare phenotypic variation with environmental variation, testing whether changes in the environment correlate with changes in the trait.
Estimate the proportion of phenotypic variance attributable to environmental factors versus genetic factors by partitioning variance components, often using models such as the linear mixed model or the breeder's equation.
Interpret the results to determine if environmental factors significantly impact the phenotype, considering the possibility of gene-environment interactions that may modify the expression of the quantitative trait.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Quantitative Inheritance
Quantitative inheritance refers to traits controlled by multiple genes, each contributing a small effect, resulting in continuous variation (e.g., height or skin color). These traits do not follow simple Mendelian patterns and are influenced by both genetic and environmental factors.
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Phenotype and Environmental Influence
Phenotype is the observable characteristic of an organism, shaped by genetic makeup and environmental conditions. Environmental factors such as nutrition, temperature, or stress can modify the expression of quantitative traits, making it essential to separate genetic effects from environmental impacts.
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Statistical Methods for Environmental Assessment
To assess environmental effects on quantitative traits, researchers use statistical tools like analysis of variance (ANOVA) and regression analysis. These methods help partition phenotypic variance into genetic and environmental components, enabling the evaluation of how much environment influences the trait.
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Related Practice
Textbook Question
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Textbook Question
How can we ascertain the number of polygenes involved in the inheritance of a quantitative trait?
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Textbook Question
What findings led geneticists to postulate the multiple-factor hypothesis that invoked the idea of additive alleles to explain inheritance patterns?
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Textbook Question
How do we know that monozygotic twins are not identical genotypically as adults?
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Textbook Question
Write a short essay that discusses the difference between the more traditional Mendelian and neo-Mendelian modes of inheritance (qualitative inheritance) and quantitative inheritance.
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Textbook Question
Define the following:
(a) Polygenic
(b) Additive alleles
(c) Correlation
(d) Monozygotic and dizygotic twins
(e) Heritability
(f) QTL
(g) Continuous variation
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