Skip to main content
Ch. 5 - Chromosome Mapping in Eukaryotes
Klug - Concepts of Genetics  12th Edition
Klug12th EditionConcepts of Genetics ISBN: 9780135564776Not the one you use?Change textbook
Chapter 5, Problem 22b

An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
Table showing progeny genotypes and counts from a testcross of AaBbCc with aabbcc, highlighting linked gene inheritance.
Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring.

Verified step by step guidance
1
Step 1: Understand the testcross setup. The organism with genotype AaBbCc is crossed with a triply recessive organism aabbcc. The progeny genotypes reflect the gametes produced by the AaBbCc parent combined with the aabbcc parent's gametes.
Step 2: Recognize that if the three genes are tightly linked with no crossover, only the parental (non-recombinant) gametes will be produced by the AaBbCc parent. This means the progeny will only show genotypes corresponding to the original parental haplotypes.
Step 3: Identify the parental haplotypes from the AaBbCc parent. Since the parent is heterozygous at all three loci, the two parental haplotypes are the combinations of alleles found together on each chromosome. For example, one chromosome might carry ABC and the other abc.
Step 4: Determine which progeny genotypes correspond to these parental haplotypes. Only progeny with genotypes matching these haplotypes (combined with the recessive aabbcc parent) will be observed if no crossover occurs.
Step 5: Conclude that the progeny genotypes that do not match the parental haplotypes represent recombinant types and would not be present if no crossover occurred. Therefore, only the progeny with genotypes corresponding to the parental haplotypes should be counted.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
1m
Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Testcross and Its Purpose

A testcross involves crossing an organism with a dominant phenotype but unknown genotype with a homozygous recessive organism. This helps reveal the genotype of the dominant parent by analyzing the phenotypes and genotypes of the offspring, especially useful for studying linked genes and recombination.
Recommended video:
Guided course
00:52
Purpose of X Inactivation

Genetic Linkage and Recombination

Genetic linkage occurs when genes are located close together on the same chromosome and tend to be inherited together. Recombination through crossing over can separate linked genes, producing new allele combinations. If no crossover occurs, only parental allele combinations appear in offspring.
Recommended video:
Guided course
07:33
Chi Square and Linkage

Interpreting Progeny Ratios in Linked Genes

Progeny genotype frequencies from a testcross can indicate linkage and crossover events. Equal numbers of parental types and fewer recombinants suggest linkage with some crossing over. If no recombinants are observed, all offspring genotypes correspond to parental haplotypes, indicating very tight linkage.
Recommended video:
Guided course
07:56
Sex-Linked Genes
Related Practice
Textbook Question

Are mitotic recombinations and sister chromatid exchanges effective in producing genetic variability in an individual? in the offspring of individuals?

492
views
Textbook Question

What possible conclusions can be drawn from the observations that in male Drosophila, no crossing over occurs, and that during meiosis, synaptonemal complexes are not seen in males but are observed in females where crossing over occurs?

499
views
Textbook Question

An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.

If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair?

927
views
Textbook Question

An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.

What can you conclude from the actual data about the location of the three genes in relation to one another?

917
views
Textbook Question

Based on our discussion of the potential inaccuracy of mapping, would you revise your answer to Problem 22? If so, how?

604
views
Textbook Question

Traditional gene mapping has been applied successfully to a variety of organisms including yeast, fungi, maize, and Drosophila. However, human gene mapping has only recently shared a similar spotlight. What factors have delayed the application of traditional gene-mapping techniques in humans?

526
views