Textbook Question
Identify two differences in chemical composition that distinguish DNA from RNA.
603
views
Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
Not the one you use?Change textbookSelect a different textbook
Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
All textbooks
Sanders 3rd EditionCh. 1 - The Molecular Basis of Heredity, Variation, and EvolutionProblem 20a
Sanders 3rd EditionCh. 1 - The Molecular Basis of Heredity, Variation, and EvolutionProblem 20aChapter 1, Problem 20a
The following segment of DNA is the template strand transcribed into mRNA:
5'-...GACATGGAA...-3'
What is the sequence of mRNA created from this sequence?
Verified step by step guidance1
Identify the direction of the DNA template strand. The given DNA template strand is 5'-...GACATGGAA...-3'. Remember that transcription occurs in the 5' to 3' direction of the mRNA, which is complementary to the 3' to 5' direction of the DNA template strand.
Determine the complementary base pairing rules for transcription. In RNA, adenine (A) pairs with uracil (U), thymine (T) pairs with adenine (A), cytosine (C) pairs with guanine (G), and guanine (G) pairs with cytosine (C).
Using the base pairing rules, transcribe the DNA template strand into the mRNA sequence. For each base in the DNA template strand, write the complementary RNA base. For example, G in the DNA pairs with C in the RNA, A in the DNA pairs with U in the RNA, and so on.
Reverse the sequence of the transcribed mRNA to ensure it is written in the 5' to 3' direction, as mRNA is synthesized in this orientation during transcription.
Write the final mRNA sequence in the 5' to 3' direction, ensuring that all bases are correctly transcribed and oriented.
Verified video answer for a similar problem:
This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
1mWas this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Transcription
Transcription is the process by which the genetic information in DNA is copied into messenger RNA (mRNA). During this process, RNA polymerase binds to the DNA template strand and synthesizes a complementary RNA strand. The RNA is synthesized in the 5' to 3' direction, meaning that the RNA strand will have a sequence that is complementary to the DNA template strand.
Recommended video:
Guided course
09:16
Eukaryotic Transcription
Base Pairing Rules
Base pairing rules dictate how nucleotides pair in DNA and RNA. In DNA, adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). However, in RNA, uracil (U) replaces thymine, so adenine pairs with uracil. Understanding these rules is essential for determining the correct mRNA sequence from a given DNA template.
Recommended video:
Guided course
03:49Base Distortions
5' to 3' Directionality
Nucleic acids, including DNA and RNA, have directionality, indicated as 5' and 3' ends. The 5' end has a phosphate group, while the 3' end has a hydroxyl group. During transcription, RNA is synthesized in the 5' to 3' direction, meaning that the RNA strand will be complementary to the DNA template strand and will start from the 3' end of the DNA template.
Recommended video:
Guided course
05:02Directionality
Related Practice
Textbook Question
What is the central dogma of biology? Identify and describe the molecular processes that accomplish the flow of genetic information described in the central dogma.
1229
views
Textbook Question
A portion of a polypeptide contains the amino acids Trp-Lys-Met-Ala-Val. Write the possible mRNA and template-strand DNA sequences. (Hint: Use A/G and T/C to indicate that either adenine/guanine or thymine/cytosine could occur in a particular position, and use N to indicate that any DNA nucleotide could appear.)
623
views
Textbook Question
The following segment of DNA is the template strand transcribed into mRNA:
5'-...GACATGGAA...-3'
What is the amino acid sequence produced by translation?
951
views
Textbook Question
Using the following amino acid sequences obtained from different species of apes, construct a phylogenetic tree of the apes.
525
views
Textbook Question
Examine the following figure and answer the following questions.
How many clades are shown in the figure?
580
views