The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes. Since few genes exist there, these regions almost never decondense for transcription. At what point during the cell cycle would you expect to observe the decondensation of heterochromatic regions? Why?

How do microRNAs regulate epigenetic mechanisms during development?

What are the functions of lncRNAs in epigenetic regulation? Describe each in detail.

What are the different chromatin classifications, and what is their relationship to gene expression?

Define epigenetics, and provide examples illustrating your definition.

What are the differences and similarities among the three classes of monoallelic gene expression?

Describe the manner in which activators and repressors influence the rate of transcription initiation. How might chromatin structure be involved in such regulation?

What is the role of imprinting in human genetic disorders?