How and why are eukaryotic mRNAs transported and localized to discrete regions of the cell?

Question

Accepted Answer

Welcome back. Let's look at our next problem. It says the M. RNA is stored within the cell in a translational e inactive state are and then we have four different answer choices. Well we need to recall that this is an abnormal situation for M. R. N. S. M. R. Nasr. Usually you transcribe your M. R. N. A. It moves from the nucleus to the cytoplasm and then it's translated. M. RNA is not very long lasting. It tends to degrade quickly. Um And so if you have M. RNA is just sitting around being stored and and not being translated there has to be something there to preserve this sort of abnormal situation. And in this case it's choice a bound to RNA binding proteins. So RNA binding proteins are associated in the cell. Typically with M. RNA is being stored there but not being translated. So let's look at our other inter choices to understand why they're not correct choice. B says bound to ribosomes. Well, the presence of Arribas on mountain M. RNA molecule would indicate that translation is taking place. So that would not be what you would see if you're looking for M. R. N. A. S. That are not being translated that are just being stored. So that's why that's not a correct answer choice. E says freely floating in the cytoplasm. Again when M. RNA is in the cytoplasm, it's typically translated. So if it's not going to be translated, it typically needs to be coupled with some sort of regulatory element like an RNA binding protein to delay translation. So that's not our answer choice since freely floating M. R. N. A. Would not be expected to be in a trans translation early inactive state. For that reason finally, twisty bound to RNA polymerase. RNA polymerase is what transcribes M. RNA from D. N. A. As we recall. And it's generally released when that process is over. So you wouldn't expect to see M. RNA is just sitting around bound to RNA polymerase. So that's why that's not a correct answer. So again, the M. RNA is stored within the cell and the translational e inactive state. Our choice a bound to RNA binding proteins. See you in the next video.

How and why are eukaryotic mRNAs transported and localized to discrete regions of the cell?

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Key Concepts

mRNA Transport Mechanisms in Eukaryotic Cells

mRNA Localization Signals and Binding Proteins

Functional Importance of mRNA Localization